Results 111 to 120 of about 448,957 (296)
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
Advanced Science, EarlyView.A novel multiple cross‐linked betaine‐type amphiphilic polymer hydrogels are developed via in situ free radical copolymerization. The resultant formation, named P(SBMA‐co‐AANa) hydrogel, functions as a vitreous substitute and demonstrates superior performance in optical properties, support capacity, and biocompatibility on a vitrectomized rabbit model.
Yuting Cai +8 more
wiley +1 more source
UNILATERAL RETINAL CHANGES in CEREBRAL HAeMORRHAGE, EMBOLISM, and THROMBOSIS [PDF]
, 1898 R. T. Williamson
openalex +1 more source
Advanced Science, EarlyView.A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana +10 more
wiley +1 more source
Purification and properties of carotene 15,15′-dioxygenase of rabbit intestine
Journal of Lipid Research, 1972 Carotene 15,15′-dioxygenase, which oxidizes carotenoids to retinal, has been purified up to 200-fold from rabbit intestine by ammonium sulfate fractionation, heat treatment, and acetone precipitation.
M.R. Lakshmanan +2 more
doaj
Recurrent Spontaneous Retinal Hemorrhage of Probable Tubercular Origin [PDF]
, 1919 Robert H. Buck
openalex +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Advanced Science, EarlyView.Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia +29 more
wiley +1 more source
Role of P2X7R in Retinal Diseases: A Review
Immunity, Inflammation and DiseaseBackground P2X purinoceptor 7 receptor (P2X7R) is an ATP‐gated ion channel that, upon activation by ATP, triggers the release of inflammatory mediators and induces apoptosis in cells.
Chunli Li, Binsheng Wang
doaj +1 more source