Results 171 to 180 of about 1,135,598 (287)

Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines

Development, 2019
E. Capowski, K. Samimi, Steven J. Mayerl, M. Phillips, I. Pinilla, S. Howden, S. Howden, J. Saha, Alex D. Jansen, Kimberly L. Edwards, Lindsey D. Jager, Katherine Barlow, Rasa Valiauga, Z. Erlichman, Anna Hagstrom, Divya Sinha, Valentin M. Sluch, Xitiz Chamling, D. Zack, M. Skala, M. Skala, D. Gamm   +21 more
semanticscholar   +1 more source

Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1

Advanced Science, EarlyView.
TREX1 antagonizes DNA sensor cGAS by degrading cytosolic DNA. This work identifies gigaxonin as a molecular switch that coordinates DNA sensing and clearance pathways to amplify antiviral responses. Under the steady state, gigaxonin maintains cellular homeostasis by mediating TREX1 ubiquitination and proteasomal degradation. During DNA virus infection,
Ben‐Zhe Ji, Jie Wang, Yi Tu, Shan Zhang, Yong‐Sheng Wei, Yan He, Bin Zhang, Qing‐Qing Zhao, Hao‐Min Hu, Yu Liu   +9 more
wiley   +1 more source

Schisis-Like Presentations of Familial Exudative Vitreoretinopathy Caused by <i>FZD4</i> Mutations. [PDF]

J Vitreoretin Dis
Shah S, da Cruz NFS, Sengillo J, Fan J, Staropoli P, Lopez-Font F, Negron C, Berrocal AM.   +7 more
europepmc   +1 more source

Retinal pigment epithelium, age-related macular degeneration and neurotrophic keratouveitis

, 2012
Enrica Bianchi, Fabio Scarinci, Guido Ripandelli, János Fehér, Elena Pacella, Giuseppe Magliulo, C. Balacco Gabrieli, Rocco Plateroti, Pasquale Plateroti, Fiorenzo Mignini, Marco Artico   +10 more
openalex   +2 more sources

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

Advanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song, Zilv Mei, Qijie Zheng, Qingqing Yuan, Yu Liang, Jiaqi Gao, Lang Zhou, Shuheng Wu, Wei Wu   +8 more
wiley   +1 more source

Application of ultra-wide-field optical coherence tomography angiography in detecting peripheral lattice degeneration. [PDF]

Int Ophthalmol
Cai C, Liu P, Wei Q, Huang J, Yi L, Wei F, Qiu Q, Song C.   +7 more
europepmc   +1 more source

PI3K/AKT/mTOR signaling pathway inhibitors in proliferation of retinal pigment epithelial cells.

, 2012
Na Cai, Shun‐Dong Dai, Ningning Liu, Limin Liu, Ning Zhao, Lei Chen   +5 more
openalex   +2 more sources

Contribution of Multifocal Electroretinography and Optical Coherence Tomography in Predicting the Visual Prognosis of Rhegmatogenous Retinal Detachment [PDF]

, 2013
Sami Yılmaz, Özgür Yalçınbayır, Remzi Avcı, Berkant KADERLİ, Özgür Bülent Timuçin   +4 more
openalex   +1 more source

Microglia Drive Peripapillary Vascular Density Reduction in Normal Tension Glaucoma by Regulating the Rpl17/Stat5b/Apoa1 Axis

Advanced Science, EarlyView.
This study revealed that E50K mutant microglia drive retinal peripapillary vascular density reduction in NTG via the Rpl17/Stat5b/Apoa1 axis and identified Apoa1 as a novel suppressor of retinal vascular endothelial cells. These findings identify a potential therapeutic target for glaucoma and support the clinical potential of EA for protecting RGCs ...
Di Zhang, Sisi Chen, Yanfeng Zhang, Leyi Qiu, Mengxian Du, Wulian Song, Fengyi Guo, Jingyang Zhang, Xinna Liu, Huiping Yuan   +9 more
wiley   +1 more source

A NOVEL USE OF FINESSE FLEX LOOP FOR PROLIFERATIVE VITREORETINOPATHY. [PDF]

Retin Cases Brief Rep
Erakgun T.
europepmc   +1 more source