Results 191 to 200 of about 498,360 (318)

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen   +9 more
wiley   +1 more source

Two cases of juxtapapillary retinal astrocytic hamartoma: a multimodal imaging study. [PDF]

open access: yesBMC Ophthalmol
Mitamura M   +4 more
europepmc   +1 more source

Bidirectional Photoadaptive Organic Heterojunction Synaptic Transistors for Accurate Image Recognition in Machine Vision Systems

open access: yesAdvanced Science, EarlyView.
Bidirectional photoadaptive organic synaptic phototransistors are developed using complementary n–n and n‐p heterojunctions. These devices enable intelligent in‐sensor processing, markedly enhancing image contrast and edge features under adverse lighting, and achieve a recognition accuracy of 97.4% within ten training cycles for machine vision ...
Di Xue   +9 more
wiley   +1 more source

Glucocorticoids exert differential effects on the endothelium in an in vitro model of the blood–retinal barrier [PDF]

open access: bronze, 2018
Anne‐Eva van der Wijk   +6 more
openalex   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

open access: yesAdvanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown   +3 more
wiley   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang   +2 more
wiley   +1 more source

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