Results 141 to 150 of about 39,677 (234)
GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley +1 more source
Conservation of Neuron‐Astrocyte Correlated Activity in Developing Sensory Pathways
Astrocytes and neurons in the superior colliculus exhibit spatiotemporal correlated activity before eye opening. Each neuronal wave is followed by a calcium wave in astrocytes. Spillover of glutamate activates mGluR5 and mGluR3 in astrocytes. ABSTRACT Neurons in developing sensory organs exhibit prolonged burst firing before the onset of sensory ...
Vered Kellner +8 more
wiley +1 more source
A model of ganglion axon pathways accounts for percepts elicited by retinal implants. [PDF]
Degenerative retinal diseases such as retinitis pigmentosa and macular degeneration cause irreversible vision loss in more than 10 million people worldwide.
Beyeler, Michael +5 more
core
Field‐free programmable bipolar magnetic heterostructures for neuromorphic computing
Neuromorphic computing mimics the brain's efficiency, yet typical memristors lack biological synapses' dual signal control. We introduce a magnetic memristor enabling bidirectional, multi‐state modulation without external fields, validated in image feature extraction and neural clustering.
Yaping He +9 more
wiley +1 more source
LRRTM4: A Novel Regulator of Presynaptic Inhibition and Ribbon Synapse Arrangements of Retinal Bipolar Cells. [PDF]
Sinha R +9 more
europepmc +1 more source
Cyclic GMP in the pig vitreous and retina after experimental retinal detachment [PDF]
Purpose: Earlier studies have revealed a decreased level of cGMP in vitreous fluid obtained from patients with a retinal detachment. To further investigate this phenomenon, we developed an experimental retinal detachment model in pigs.
Diederen, R. +5 more
core
A safe, transparent, invisible flickering transparent white OLED (TrWOLED) platform is developed for therapeutic 40 Hz brain stimulation. By utilizing chromatic modulation, this device delivers effective gamma frequency brain entrainment while eliminating visual fatigue.
Younghun Jung +2 more
wiley +1 more source
Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: electron microscopy, tomography and oxygen consumption. [PDF]
PurposePostnatal lead exposure produces rod-selective and Bax-mediated apoptosis, decreased scotopic electroretinograms (ERGs), and scotopic and mesopic vision deficits in humans and/or experimental animals.
Ellisman, Mark H +5 more
core +1 more source
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld +5 more
wiley +1 more source
A prospective cohort study assessed 28 children with substantial prenatal alcohol exposure (PAE) and 52 controls at the age of 6. Most PAE children met Fetal Alcohol Spectrum Disorder (FASD) criteria, showing dysmorphic features, neurocognitive deficits, ADHD symptoms, and other health impairments. None had a prior diagnosis, demonstrating the need for
M. Jolma +5 more
wiley +1 more source

