Cis-regulatory basis of sister cell type divergence in the vertebrate retina [PDF]
eLife, 2019 Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood.
Daniel P Murphy +4 more
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Cell Type-Selective Loss of Peroxisomal β-Oxidation Impairs Bipolar Cell but Not Photoreceptor Survival in the Retina [PDF]
Cells, 2022 Retinal degeneration is a common feature in peroxisomal disorders leading to blindness. Peroxisomes are present in the different cell types of the retina; however, their precise contribution to retinal integrity is still unclear.
Daniëlle Swinkels +7 more
doaj +2 more sources
Cone bipolar cell synapses generate transient versus sustained signals in parallel ON pathways of the mouse retina [PDF]
eLifeParallel processing is a fundamental organizing principle in the nervous system and understanding how parallel neural circuits generate distinct outputs from common inputs is a key goal of neuroscience. In the mammalian retina, divergence of cone signals
Sidney P Kuo +8 more
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Forming Metallic Micro-Feature Bipolar Plates for Fuel Cell Using Combined Hydroforming and Stamping Processes [PDF]
Iranica Journal of Energy and Environment, 2013 Fuel cell constitutes from different components, among which bipolar plates are the important and expensive part. Nowadays, the fabrication methods of bipolar plates are the main challenges in fuel cell technology.
Moosa Balali Osia +3 more
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Temporal order of bipolar cell genesis in the neural retina
Neural Development, 2008 Background Retinal bipolar cells comprise a diverse group of neurons. Cone bipolar cells and rod bipolar cells are so named for their connections with cone and rod photoreceptors, respectively.
Chen C-M Amy +2 more
doaj +3 more sources
Cholinergic feedback to bipolar cells contributes to motion detection in the mouse retina
Cell Reports, 2021 Summary: Retinal bipolar cells are second-order neurons that transmit basic features of the visual scene to postsynaptic partners. However, their contribution to motion detection has not been fully appreciated.
Chase B. Hellmer +5 more
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Robust cone-mediated signaling persists late into rod photoreceptor degeneration
eLife, 2022 Rod photoreceptor degeneration causes deterioration in the morphology and physiology of cone photoreceptors along with changes in retinal circuits. These changes could diminish visual signaling at cone-mediated light levels, thereby limiting the efficacy
Miranda L Scalabrino +7 more
doaj +1 more source
Metabotropic Glutamate Receptors at Ribbon Synapses in the Retina and Cochlea
Cells, 2022 Our senses define our view of the world. They allow us to adapt to environmental stimuli and are essential for communication and social behaviour. For most humans, seeing and hearing are central senses for their daily life.
Lisa Klotz-Weigand, Ralf Enz
doaj +1 more source
Regulation of ON bipolar cell activity [PDF]
Progress in Retinal and Eye Research, 2008 Synaptic transmission from photoreceptors to all types of ON bipolar cells is primarily mediated by the mGluR6 receptor. This receptor, which is apparently expressed uniquely in the nervous system by ON bipolar cells, couples negatively to a nonselective cation channel.
Josefin, Snellman +3 more
openaire +2 more sources
Light-dependent changes in the outer plexiform layer of the mouse retina
Frontiers in Ophthalmology, 2023 The ability of the visual system to relay meaningful information over a wide range of lighting conditions is critical to functional vision, and relies on mechanisms of adaptation within the retina that adjust sensitivity and gain as ambient light changes.
Tammie L. Haley +6 more
doaj +1 more source