Results 31 to 40 of about 263,731 (299)
A systematic comparison of optogenetic approaches to visual restoration
Molecular Therapy: Methods & Clinical Development, 2022 During inherited retinal degenerations (IRDs), vision is lost due to photoreceptor cell death; however, a range of optogenetic tools have been shown to restore light responses in animal models. Restored response characteristics vary between tools and the
Michael J. Gilhooley +5 more
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Chinese Science Bulletin, 1999 Being the functional basis of neural networks, neuronal signal integration has been currently becoming a hot point of neuroscience research. Active and passive membrane properties of retinal bipolar cells, temporal and spatial distribution of synaptic inputs to these cells are described, and modulation of signal integration characteristics of these ...
Jiulin Du, Xiongli Yang
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Life cycle assessment of geopolymer concrete: A Malaysian context [PDF]
, 2001 An electrochemical fuel cell contains first and second monolithic electrically conducting flow field-bipolar plate assemblies arranged essentially parallel to each other such that an inside surface of the first bipolar separator plate is facing an inside
McGrath, Teresa +5 more
core +2 more sources
A transgenic mouse line expressing cre recombinase in undifferentiated postmitotic mouse retinal bipolar cell precursors. [PDF]
PLoS ONE, 2011 Approaches for manipulating cell type-specific gene expression during development depend on the identification of novel genetic tools. Here, we report the generation of a transgenic mouse line that utilizes Vsx2 upstream sequences to direct Cre ...
Philip E B Nickerson +5 more
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Frontiers in Cellular Neuroscience, 2022 Bipolar cells have become successful targets for optogenetic gene therapies that restore vision after photoreceptor degeneration. However, degeneration was shown to cause changes in neuronal connectivity and protein expression, which may impact the ...
Giulia Schilardi, Sonja Kleinlogel
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RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells. [PDF]
, 2015 A subset of retinal ganglion cells is intrinsically photosensitive (ipRGCs) and contributes directly to the pupillary light reflex and circadian photoentrainment under bright-light conditions.
Berson, David M +8 more
core +2 more sources
Complexity of retinal cone bipolar cells [PDF]
Progress in Retinal and Eye Research, 2010 An open issue of retinal organization and function is the comprehension of the different tasks specifically performed by bipolar cells, the neurons that collect information from photoreceptors in the outer retina and convey the signal to the inner plexiform layer.
Strettoi E +4 more
openaire +3 more sources
Frontiers in Molecular Neuroscience, 2019 Processes of >100 types of interneurons (bipolar and amacrine cells) and projection neurons (retinal ganglion cells, RGCs) form specific and stereotyped patterns of connections in the inner plexiform layer (IPL) of the mouse retina.
Masahito Yamagata, Joshua R. Sanes
doaj +1 more source
Cell Reports, 2017 The complexity of sensory receptive fields increases from one synaptic stage to the next. In many cases, increased complexity is achieved through spatiotemporal interactions between convergent excitatory and inhibitory inputs.
James W. Fransen, Bart G. Borghuis
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Single-Flux-Quantum Bipolar Digital-to-Analog Converter Comprising Polarity-Switchable Double-Flux-Quantum Amplifier [PDF]
, 2017 We present a single-flux-quantum (SFQ)-based digital-to-analog converter (DAC) generating bipolar output voltages, in which the key component is a polarity-switchable double-flux-quantum amplifier (PS-DFQA). The DAC comprised a dc/SFQ converter, an 8-bit
Hiroshi Shimada +2 more
core +2 more sources