Results 11 to 20 of about 263,731 (299)
Transience of the Retinal Output Is Determined by a Great Variety of Circuit Elements
Cells, 2022 Retinal ganglion cells (RGCs) encrypt stimulus features of the visual scene in action potentials and convey them toward higher visual centers in the brain.
Alma Ganczer +7 more
doaj +1 more source
GABAA presynaptic inhibition regulates the gain and kinetics of retinal output neurons
eLife, 2021 Output signals of neural circuits, including the retina, are shaped by a combination of excitatory and inhibitory signals. Inhibitory signals can act presynaptically on axon terminals to control neurotransmitter release and regulate circuit function ...
Jenna Nagy +3 more
doaj +1 more source
eLife, 2020 While multicompartment models have long been used to study the biophysics of neurons, it is still challenging to infer the parameters of such models from data including uncertainty estimates.
Jonathan Oesterle +8 more
doaj +1 more source
Rod and Cone Connections With Bipolar Cells in the Rabbit Retina
Frontiers in Cellular Neuroscience, 2021 Rod and cone pathways are segregated in the first stage of the retina: cones synapse with both ON- and OFF-cone bipolar cells while rods contact only rod bipolar cells.
Christopher M. Whitaker +3 more
doaj +1 more source
Fabrication of PEM Fuel Cell Bipolar Plates by Indirect SLS [PDF]
, 2004 The paper presents a new manufacturing technique involving Selective Laser Sintering (SLS) for proton exchange membrane fuel cell (PEMFC) bipolar plate fabrication.
Bourell, David L. +2 more
core +1 more source
Frontiers in Cellular Neuroscience, 2021 A chemical synapse is either an action potential (AP) synapse or a graded potential (GP) synapse but not both. This study investigated how signals passed the glutamatergic synapse between the rod photoreceptor and its postsynaptic hyperpolarizing bipolar
Ji-Jie Pang, Fan Gao, Samuel M. Wu
doaj +1 more source
Differential function of Gγ13 in rod bipolar and ON cone bipolar cells [PDF]
The Journal of Physiology, 2015 Key points The G‐protein‐mediated metabotropic glutamate receptor 6 (mGluR6) signalling cascade is critical for light responses in all retinal ON bipolar cells. The present study evaluates the role of G‐protein subunit Gγ13 in ON bipolar cells by deleting the mouse Gng13 gene.
Hariharasubramanian, Ramakrishnan +6 more
openaire +2 more sources
Connectivity map of bipolar cells and photoreceptors in the mouse retina
eLife, 2016 In the mouse retina, three different types of photoreceptors provide input to 14 bipolar cell (BC) types. Classically, most BC types are thought to contact all cones within their dendritic field; ON-BCs would contact cones exclusively via so-called ...
Christian Behrens +4 more
doaj +1 more source
Ccl5 Mediates Proper Wiring of Feedforward and Lateral Inhibition Pathways in the Inner Retina
Frontiers in Neuroscience, 2018 The β-chemokine Ccl5 and its receptors are constitutively expressed in neurons of the murine inner retina. Here, we examined the functional and structural significance of this constitutive Ccl5 signaling on retinal development.
D’Anne S. Duncan +10 more
doaj +1 more source
Cells, 2020 More than 1.5 million people suffer from Retinitis Pigmentosa, with many experiencing partial to complete vision loss. Regenerative therapies offer some hope, but their development is challenged by the limited regenerative capacity of mammalian model ...
Abirami Santhanam +5 more
doaj +1 more source