Results 111 to 120 of about 125,005 (308)

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Voluntary running delays primary degeneration in rat retinas after partial optic nerve transection

Neural Regeneration Research, 2019
Running is believed to be beneficial for human health. Many studies have focused on the neuroprotective effects of voluntary running on animal models. There were both primary and secondary degeneration in neurodegenerative diseases, including glaucoma ...
Hong-Ying Li, Xi Hong, Mi Huang, Kwok-Fai So   +3 more
doaj   +1 more source

Physiopathology of retinal degeneration in rd1 mouse model of retinitis pigmentosa TGF-Β1, proteinases and oxidative stress mechanisms

, 2009
The rd1 (retinal degeneration) mouse retina shows degeneration homologous to a form of retinitis pigmentosa with a rapid loss of rod photoreceptors and deficiency of retinal blood vessels.
Caffé, Romeo A.,, Ekström, Per,, Ahuja, Sat pal,, Veen, Theo Van,, Lund University., Ahuja-Jensen, Poonam,, Abrahamson, Magnus,   +6 more
core  

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Mesenchymal stem cell–derived small extracellular vesicles enhance the therapeutic effect of retinal progenitor cells in retinal degenerative disease rats

Neural Regeneration Research
Our previous study demonstrated that combined transplantation of bone marrow mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal degeneration that are superior to transplantation of retinal progenitor cells ...
Chunge Ren, Min Chen, Bangqi Ren, Yuxiao Zeng, Qiang Tan, Qiyou Li, Xue Zhang, Yajie Fang, Yixiao Zhou, Weitao Zhang, Fang Chen, Baishijiao Bian, Yong Liu   +12 more
doaj   +1 more source

Methylnitrosourea (MNU)-induced retinal degeneration and regeneration in the zebrafish: histological and functional characteristics.

, 2014
Retinal degenerative diseases, e.g. retinitis pigmentosa, with resulting photoreceptor damage account for the majority of vision loss in the industrial world. Animal models are of pivotal importance to study such diseases.
Maurer, Ellinor, Jazwinska, Anna, Enzmann, Volker, Sallin, Pauline, Tschopp, Markus, Tappeiner, Christoph   +5 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Histone Deacetylase: Therapeutic Targets in Retinal Degeneration

, 2015
The 16th International Symposium on Retinal Degeneration (RD2014), Pacific Grove, California, United States of America, 13-18 July 2014Previous studies report that retinitis pigmentosa (RP) patients treated with the histone deacetylase inhibitor (HDACi ...
Conor Daly, Jun Yin, Daly, Conor, Yin, Jun, Kennedy, Breandán, Breandán N. Kennedy   +5 more
core   +1 more source

Energy Landscapes in Chemical Reactions and Transport

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
Kinetics/dynamics of chemical reactivity and transport of chemical species in a solid are both determined by the energy landscape in which they take place. Discussing common grounds but also distinct differences may help in advancing the understanding in both fields.
Karl‐Michael Weitzel
wiley   +1 more source

Retinal degeneration mutation in Sftpa1tm1Kor/J and Sftpd -/- targeted mice.

PLoS ONE, 2018
Surfactant proteins are important collectin immune molecules with a wide distribution throughout the body, including the ocular system. Mice with gene deletions for the surfactant protein genes Sftpa1 and Sftpd were observed to have visual impairment and
Faizah Bhatti, Johannes W Kung, Frederico Vieira   +2 more
doaj   +1 more source