Results 261 to 270 of about 640,739 (357)

Mouse NR2E3^R296Q Mutation Disrupts Photoreceptor Developmental Paradigm and Leads to Early-Onset Progressive Retinal Degeneration by Suppressing RXRG Signaling. [PDF]

FASEB J
Jin J, Wang S, Huang Y, Xie S.
europepmc   +1 more source

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

Acta Ophthalmologica, EarlyView.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia, José Manuel Benítez del Castillo, Margarita Calonge, Christophe Baudouin, Marc Labetoulle   +4 more
wiley   +1 more source

Deep learning model for detecting cystoid fluid collections on optical coherence tomography in X‐linked retinoschisis patients

Acta Ophthalmologica, EarlyView.
Abstract Purpose To validate a deep learning (DL) framework for detecting and quantifying cystoid fluid collections (CFC) on spectral‐domain optical coherence tomography (SD‐OCT) in X‐linked retinoschisis (XLRS) patients. Methods A no‐new‐U‐Net model was trained using 112 OCT volumes from the RETOUCH challenge (70 for training and 42 for internal ...
Jonathan Hensman, Yasmine el Allali, Hind Almushattat, Coen de Vente, Clara I. Sánchez, Camiel J. F. Boon   +5 more
wiley   +1 more source

Regulatory T cell expansion prevents retinal degeneration in type 2 diabetes. [PDF]

J Neuroinflammation
Llorián-Salvador M, Pérez-Martínez D, Tang M, Duarri A, García-Ramirez M, Deàs-Just A, Álvarez-Guaita A, Ramos-Pérez L, Bogdanov P, Gomez-Sanchez JA, Stitt AW, Hernández C, de la Fuente AG, Simó R.   +13 more
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

All-in-one AAV-mediated Nrl gene inactivation rescues retinal degeneration in Pde6a mice. [PDF]

JCI Insight
Liu Z, Chen S, Lo CH, Wang Q, Sun Y.
europepmc   +1 more source

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou, Li Dong, Yu‐Hang Yang, Yuan He, Xiao‐Zhen Wang, Han‐Qing Zhao, Rui‐Heng Zhang, Jost B. Jonas, Wen‐Bin Wei   +8 more
wiley   +1 more source

Presumed hereditary retinal degenerations: Ibadan experience

, 2005
A O Ashaye
openalex   +2 more sources

Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration

Proceedings of the National Academy of Sciences of the United States of America, 2015
Hiroshi Shirai, M. Mandai, Keizo Matsushita, Atsushi Kuwahara, S. Yonemura, Tokushige Nakano, Juthaporn Assawachananont, Toru Kimura, Koichi Saito, H. Terasaki, Mototsugu Eiraku, Y. Sasai, Masayo Takahashi   +12 more
semanticscholar   +1 more source

Retraction Note: Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations. [PDF]

Gene Ther
Sun X, Pawlyk B, Xu X, Liu X, Bulgakov OV, Adamian M, Sandberg MA, Khani SC, Tan M-, Smith AJ, Ali RR, Li T.   +11 more
europepmc   +1 more source