Results 51 to 60 of about 640,739 (357)

Coexistence of Peripheral Retinal Diseases with Macular Hole

Türk Oftalmoloji Dergisi, 2019
Objectives:To investigate the frequency of retinal tear, retinal hole, and lattice degeneration in peripheral retinal examination of patients with macular hole.Materials and Methods:The files of patients who underwent pars plana vitrectomy surgery with a
Erdoğan Yaşar, Nazmiye Erol, Mustafa Değer Bilgeç, Ayşe İdil Çakmak   +3 more
doaj   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source

Peripapillary Intravitreal Injection Improves AAV-Mediated Retinal Transduction

Molecular Therapy: Methods & Clinical Development, 2020
The intravitreal (IVT) injection method is a choice when targeting the inner retina for gene therapy. However, the transduction efficiency of adeno-associated virus (AAV) vectors administered by the IVT route is usually low and may be affected by several
Sanjar Batirovich Madrakhimov, Jin Young Yang, Dong Hyuck Ahn, Jung Woo Han, Tae Ho Ha, Tae Kwann Park   +5 more
doaj  

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

IGF-1, Inflammation and Retinal Degeneration: A Close Network

Frontiers in Aging Neuroscience, 2018
Retinal degenerative diseases are a group of heterogeneous diseases that include age-related macular degeneration (AMD), retinitis pigmentosa (RP), and diabetic retinopathy (DR).
A. Arroba, A. Campos‐Caro, M. Aguilar-Diosdado, Á. Valverde   +3 more
semanticscholar   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Degeneration-Dependent Retinal Remodeling: Looking for the Molecular Trigger

Frontiers in Neuroscience, 2020
Vision impairment and blindness in humans are most frequently caused by the degeneration and loss of photoreceptor cells in the outer retina, as is the case for age-related macular degeneration, retinitis pigmentosa, retinal detachment and many other ...
Michael Telias, Scott Nawy, Richard H. Kramer, Richard H. Kramer   +3 more
doaj   +1 more source

Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance The retinal pigment epithelium and the choroid are complex tissues whose dysfunction can lead to irreversible visual loss. In this study, single-cell RNA sequencing of both of these tissues was performed to characterize gene expression ...
Andrew P. Voigt, Kelly Mulfaul, Nathaniel K. Mullin, Miles J. Flamme-Wiese, Joseph C. Giacalone, E. Stone, B. Tucker, T. Scheetz, R. Mullins   +8 more
semanticscholar   +1 more source

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

Advanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini, Mariarosaria De Simone, Martina Blasio, Claudia Zenna, Angela Tino, Eleni Stavrinidou, Silvia Santillo, Claudia Tortiglione   +7 more
wiley   +1 more source

Fine-tuning FAM161A gene augmentation therapy to restore retinal function

EMBO Molecular Medicine
For 15 years, gene therapy has been viewed as a beacon of hope for inherited retinal diseases. Many preclinical investigations have centered around vectors with maximal gene expression capabilities, yet despite efficient gene transfer, minimal ...
Yvan Arsenijevic, Ning Chang, Olivier Mercey, Younes El Fersioui, Hanna Koskiniemi-Kuendig, Caroline Joubert, Alexis-Pierre Bemelmans, Carlo Rivolta, Eyal Banin, Dror Sharon, Paul Guichard, Virginie Hamel, Corinne Kostic   +12 more
doaj   +1 more source