Results 61 to 70 of about 125,005 (308)

Inhibition of inflammatory cells delays retinal degeneration in experimental retinal vein occlusion in mice [PDF]

, 2020
The role of microglia in retinal inflammation is still ambiguous. Branch retinal vein occlusion initiates an inflammatory response whereby resident microglia cells are activated.
Martin S. Zinkernagel, Liu, Xuan, Zinkernagel, Martin S., Xuan Liu, Kokona, Despina, Jovanovic, Joël, Despina Kokona, Andreas Ebneter, Ebneter, Andreas, Joël Jovanovic   +9 more
core   +1 more source

Vision‐Augmented Wearable Interfaces: Bioinspired Approaches for Realistic AI‐Human‐Machine Interaction

Advanced Materials Technologies, EarlyView.
This review presents recent progress in vision‐augmented wearable interfaces that combine artificial vision, soft wearable sensors, and exoskeletal robots. Inspired by biological visual systems, these technologies enable multimodal perception and intelligent human–machine interaction.
Jihun Lee, Gwuidong Ryu, Kisoo Kim, Feng Xu, Won Gu Lee   +4 more
wiley   +1 more source

Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation

, 2014
The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Jessica Cooke (637632), Jennifer Scott, Heather Thomson, Xiaoli Chen, Lotery, Andrew J., Xiaoli Chen (102563), Cooke, J.J., Scott, Jennifer A., Andrew Lotery, Heather Thomson (637631), Thomson, Heather, Jessica Cooke, Parwez Hossain, Jennifer Scott (637633), Chen, Xiaoli, Hossain, Parwez, Andrew Lotery (637635), Parwez Hossain (637634)   +17 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Induced pluripotent stem cells and derivative photoreceptor precursors as therapeutic cells for retinal degenerations

Tzu Chi Medical Journal, 2020
The visual impairment associated with inherited retinal degeneration and age-related degeneration of photoreceptors is causing substantial challenges in finding effective therapies.
Rupendra Shrestha, Yao-Tseng Wen, Rong-Kung Tsai   +2 more
doaj   +1 more source

Maturation and Protection Effect of Retinal Tissue-Derived Bioink for 3D Cell Printing Technology

Pharmaceutics, 2021
Retinal degeneration is a leading cause of incurable vision loss and blindness. The increasing incidence of retinal degeneration has triggered research into the development of in vitro retinal models for drug development and retinal alternatives for ...
Jongmin Kim, Jeong Sik Kong, Hyeonji Kim, Wonil Han, Jae Yon Won, Dong-Woo Cho   +5 more
doaj   +1 more source

Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision

, 2012
Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Shivaranjani Shivalingaiah, Samarendra Mohanty, Mathew Ficinski, Ling Gu, Edward Wong   +4 more
core   +1 more source

Candidate gene study of macular response to supplemental lutein and zeaxanthin. [PDF]

, 2013
Supplementation with carotenoids is proposed to protect against age-related macular degeneration. There is, however, considerable variability in retinal macular pigment response, which may be due to underlying genetic variation. The purpose of this study
Liew, SH Melissa, Venturini, Cristina, Williams, Katherine; id_orcid, Beatty, Stephen, Hysi, Pirro G., Williams, Katie M., Gilbert, Clare E, Gilbert, Clare E., Hysi, Pirro G, Williams, Katie M, Nag, Abhishek, Hammond, Christopher J., Liew, S.H. Melissa, Yonova-Doing, Ekaterina, Hammond, Christopher J, Liew, S H Melissa   +15 more
core   +1 more source

Protein Misfolding and Retinal Degeneration [PDF]

Cold Spring Harbor Perspectives in Biology, 2011
The retina is a highly complex and specialized organ that performs preliminary analysis of visual information. Composed of highly metabolically active tissue, the retina requires a precise and well-balanced means of maintaining its functional activity during extended periods of time.
Radouil, Tzekov, Linda, Stein, Shalesh, Kaushal   +2 more
openaire   +2 more sources

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source