The Gibbs-plaid biclustering model [PDF]
We propose and develop a Bayesian plaid model for biclustering that accounts for the prior dependency between genes (and/or conditions) through a stochastic relational graph. This work is motivated by the need for improved understanding of the molecular mechanisms of human diseases for which effective drugs are lacking, and based on the extensive raw ...
arxiv +1 more source
Machine Learning Method for Functional Assessment of Retinal Models [PDF]
Challenges in the field of retinal prostheses motivate the development of retinal models to accurately simulate Retinal Ganglion Cells (RGCs) responses. The goal of retinal prostheses is to enable blind individuals to solve complex, reallife visual tasks.
arxiv +1 more source
Establishing an experimental rat model of photodynamically-induced retinal vein occlusion using erythrosin B [PDF]
AIM:To develop a reliable, reproducible rat model of retinal vein occlusion (RVO) with a novel photosensitizer (erythrosin B) and study the cellular responses in the retina.METHODS:Central and branch RVOs were created in adult male rats via ...
Mi Zheng+5 more
core +1 more source
Exudative Retinal Detachment Treatment in a Patient with Thrombotic Thrombocytopenic Purpura
Purpose: We report a case of unilateral exudative retinal detachment in a patient with thrombotic thrombocytopenic purpura (TTP), without associated hypertension, successfully treated with plasmapheresis.
Magali Sampo+5 more
doaj +1 more source
Point-of-care Ultrasound to Distinguish Retinal Detachment and Ruptured Arterial Microaneurysm
Case presentation: We present the case of an older male with point-of-care-ultrasound (POCUS) imaging consistent with retinal detachment who was instead found by ophthalmology to have a ruptured arterial microaneurysm with vitreous and preretinal ...
Rachel Kester+2 more
doaj +1 more source
BACKGROUND Ocular complaints are common presentations to the emergency department (ED). Among these, retinal detachment can cause significant vision loss if not rapidly diagnosed and referred for appropriate treatment.
M. Gottlieb, Dallas Holladay, G. Peksa
semanticscholar +1 more source
Bilateral Simultaneous Retinal Detachment in Pseudophakia [PDF]
Cataract surgery is the most frequent surgical intervention, with approximately 700,000 operations per year in Germany alone. One of the most serious complications is retinal detachment, with a reported incidence rate of pseudophakic retinal detachment ...
Antje Mammen+5 more
core +5 more sources
Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. [PDF]
Detachment of photoreceptors from the underlying retinal pigment epithelium is seen in various retinal disorders such as retinal detachment and age-related macular degeneration and leads to loss of photoreceptors and vision.
Dimosthenis Mantopoulos+6 more
doaj +1 more source
Fully Automated Tree Topology Estimation and Artery-Vein Classification [PDF]
We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very challenging because vessels cross each other in a 2D image, obscuring their true paths. We quantitatively validated the
arxiv
Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection
Ocular fluids from patients with retinal detachment show iron accumulation, and transferrin can be used as a therapeutic adjuvant. In retinal detachment (RD), photoreceptor death and permanent vision loss are caused by neurosensory retina separating from
A. Daruich+11 more
semanticscholar +1 more source