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International Journal of Molecular Sciences, 2022 Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of diseases that cause vision loss due to abnormal development or due to the dysfunction or degeneration of the photoreceptors or the retinal pigment epithelium [...].
T. Ben-Yosef
semanticscholar +3 more sources
Diagnosis of Inherited Retinal Diseases Diagnose erblicher Netzhauterkrankungen [PDF]
Klinische Monatsblätter für Augenheilkunde, 2021 Inherited retinal diseases are a frequent cause of severe visual impairment or blindness in children and adults of working age. Across this group of diseases, there is great variability in the degree of visual impairment, the impact on everyday life ...
J. Birtel +4 more
semanticscholar +4 more sources
Next-Generation Nanomedicine Approaches for the Management of Retinal Diseases
Pharmaceutics, 2023 Retinal diseases are one of the leading causes of blindness globally. The mainstay treatments for these blinding diseases are laser photocoagulation, vitrectomy, and repeated intravitreal injections of anti-vascular endothelial growth factor (VEGF) or ...
Binapani Mahaling +8 more
semanticscholar +1 more source
International Journal of Clinical Practice, 2023 Purpose. This study was carried out to evaluate the visual acuity (VA), complications, and prognosis of patients diagnosed with submacular hemorrhage (SMH) from polypoidal choroidal vasculopathy (PCV) and retinal arterial macroaneurysm (RAM) treated by ...
Jianhua Wu +8 more
doaj +1 more source
On Machine Learning in Clinical Interpretation of Retinal Diseases Using OCT Images
Bioengineering, 2023 Optical coherence tomography (OCT) is a noninvasive imaging technique that provides high-resolution cross-sectional retina images, enabling ophthalmologists to gather crucial information for diagnosing various retinal diseases.
P. Karn, W. Abdulla
semanticscholar +1 more source
ICL Postimplantation Decentration and Tilt in Myopic Patients with Primary Iridociliary Cysts
Journal of Ophthalmology, 2023 Purpose. To observe the decentration and tilt of implantable collamer lens (ICL) as well as possible visual effects postimplantation in primary iridociliary cysts. Methods. The present investigation was a retrospective cohort study.
Ying Wang +6 more
doaj +1 more source
Visual impairment and blindness caused by retinal diseases: A nationwide register-based study
Journal of Global Health, 2023 Background Retinal disorders cause substantial visual burden globally. Accurate estimates of the vision loss due to retinal diseases are pivotal to inform optimal eye health care planning and allocation of medical resources.
Chuandi Zhou +59 more
semanticscholar +1 more source
PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
Cell Communication and Signaling, 2021 Background Abnormal neovascularization is the most common cause of blindness, and hypoxia alters tissue metabolism, function, and morphology. HIF-1α, the transcriptional activator of VEGF, has intricate mechanisms of nuclear translocation and activation,
Lijie Dong +6 more
doaj +1 more source
Ophthalmic Genetics, 2021 Background: This study examined the frequency of inherited retinal diseases (IRDs) as the reason for blindness registrations over the last two decades and the demographic and clinical phenotypes of inherited retinal disease (IRD)-related registrations ...
Rachael C. Heath Jeffery +5 more
semanticscholar +1 more source
Inherited retinal diseases: Therapeutics, clinical trials and end points—A review
Clinical and Experimental Ophthalmology, 2021 Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders characterised by photoreceptor degeneration or dysfunction.
M. Georgiou, K. Fujinami, M. Michaelides
semanticscholar +1 more source