Results 101 to 110 of about 205,905 (259)
Coexistence of peripheral retinal diseases with macular hole [PDF]
, 2019 *Yaşar, Erdoğan ( Aksaray, Yazar )Objectives: To investigate the frequency of retinal tear, retinal hole, and lattice degeneration in peripheral retinal examination of patients with macular hole.
Erol, Nazmiye +7 more
core +1 more source
Advanced Science, EarlyView.The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui +9 more
wiley +1 more source
Advanced Science, EarlyView.Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui +3 more
wiley +1 more source
Advanced Science, EarlyView.This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley +1 more source
Gene therapy for retinal diseases
Journal of Ophthalmic and Vision Research, 2014 Gene therapy has a growing research potential particularly in the field of ophthalmic and retinal diseases owing to three main characteristics of the eye; accessibility in terms of injections and surgical interventions, its immune-privileged status facilitating the accommodation to the antigenicity of a viral vector, and tight blood-ocular barriers ...
openaire +3 more sources
Advanced Science, EarlyView.Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li +23 more
wiley +1 more source
Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7
Advanced Science, EarlyView.Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim +16 more
wiley +1 more source
Pathophysiology of Retinal Disease [PDF]
Veterinary Clinics of North America: Small Animal Practice, 1980 openaire +3 more sources
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Advanced Science, EarlyView.Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi +5 more
wiley +1 more source
Prevalence of Retinal Vascular Diseases in a Tertiary Care Hospital in Türkiye: A Hospital-Based Epidemiologic Study [PDF]
Objectives: To determine the prevalence of diabetic retinopathy (DR), retinal vein occlusion (RVO), and retinal artery occlusion (RAO) in a tertiary care hospital in Türkiye.
Gözde Orman +4 more
core +1 more source