Results 101 to 110 of about 211,361 (268)

Treatment with 670-nm light protects the cone photoreceptors from white light-induced degeneration

, 2016
The light-induced photoreceptor damage model has been used to characterise pathological mechanisms of retinal degenerative diseases and to test potential therapeutic strategies for these conditions.
Valter (Valter-Kocsi), Krisztina, Albarracin, Rizalyn   +1 more
core   +1 more source

Age effect on retina and optic disc normal values [PDF]

, 2005
Purpose: To investigate retinal thickness and optic disc parameters by the Retinal Thickness Analyzer (RTA) glaucoma program in older normal subjects and to determine any age effect.
Chryssafis, C., Hirneiß, Christoph, Neubauer, A. S., Tsinopoulos, I., Kampik, Anselm, Thiel, M.   +5 more
core   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Intravitreal Ranibizumab versus Vitreous Lavage for Postoperative Vitreous Hemorrhage in Proliferative Diabetic Retinopathy: A Randomized Controlled Trial

Drug Design, Development and Therapy
Jiaxing Chi,1,* Xiang Zhang,1,* Zetong Nie,1 Yue Pan,1 Wenbo Li,1 Bojie Hu2 1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of ...
Chi J, Zhang X, Nie Z, Pan Y, Li W, Hu B
doaj  

α-Klotho prevents diabetic retinopathy by reversing the senescence of macrophages

Cell Communication and Signaling
Background Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus (DM) and a significant cause of acquired blindness in the working-age population worldwide.
Qingbo Li, Peiyu Wang, Yi Gong, Manhong Xu, Manqiao Wang, Rong Luan, Juping Liu, Xiaorong Li, Yan Shao   +8 more
doaj   +1 more source

Management of giant retinal tears with vitrectomy, internal tamponade, and peripheral 360 degrees retinal photocoagulation

, 2003
PURPOSE: To determine the effectiveness of vitrectomy, internal tamponade, and peripheral 360 degrees retinal photocoagulation in the management of giant retinal tears (GRTs). PARTICIPANTS: Eighteen eyes of 18 consecutive patients with GRTs were operated
Bovey, E. H., Wolfensberger, T. J., Ambresin, A.   +2 more
core   +1 more source

Novel rodent models for macular research [PDF]

, 2010
BACKGROUND: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Gesine Huber, Muehlfriedel, Regine, Huber, G., Feng, Yuxi, Seeliger, M., Tanimoto, Naoyuki, Tanimoto Naoyuki, Severin Heynen, Hans-Peter Hammes, Christian Grimm, Feng, Y., Imsand Coni, Imsand, Coni, Muehlfriedel Regine, Susanne C. Beck, Huber, Gesine, Heynen, S., Grimm Christian, Regine Muehlfriedel, Huber Gesine, vom Hagen Franziska, Coni Imsand, Imsand, C., Seeliger Mathias W., Mühlfriedel, R., Peichl, Leo, Mathias W Seeliger, vom Hagen, F., Mühlfriedel, Regine, Tanimoto, N., Heynen Severin, Hammes, Hans-Peter, Seeliger, Mathias W, Beck Susanne C., Seeliger, Mathias W., Peichl Leo, Yuxi Feng, Peichl, L., Beck, Susanne C; https://orcid.org/, Grimm, C., Feng Yuxi, Mathias W. Seeliger, Leo Peichl, Franziska vom Hagen, Grimm, Christian, Grimm, Christian; https://orcid.org/, vom Hagen, Franziska, Beck, S., Beck, Susanne Christiane, Hammes Hans-Peter, Susanne C Beck, Naoyuki Tanimoto, Hammes, H., Heynen, Severin   +53 more
core   +1 more source

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

Advanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang   +3 more
wiley   +1 more source

RETINAL NEOVASCULARIZATION SECONDARY TO PROLIFERATIVE DIABETIC RETINOPATHY CHARACTERIZED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

, 2013
Purpose: the purpose of this study was to characterize diabetic retinal neovascularization (NV) and accompanying retinal and vitreal morphologic changes using high-resolution spectral domain optical coherence tomography.Methods: A cross-sectional ...
Regiatieri, Caio V. [UNIFESP], Zhang, Jason Y., Baumal, Caroline, Cho, Hyung, Alwassia, Ahmad A., Waheed, Nadia, Duker, Jay S.   +6 more
core   +1 more source

Coexistence of peripheral retinal diseases with macular hole [PDF]

, 2019
*Yaşar, Erdoğan ( Aksaray, Yazar )Objectives: To investigate the frequency of retinal tear, retinal hole, and lattice degeneration in peripheral retinal examination of patients with macular hole.
Erol, Nazmiye, Çakmak, Ayşe İdil, Mustafa Değer Bilgeç, Bilgeç, Mustafa Değer, Erdoğan Yaşar, Ayşe İdil Çakmak, Yaşar, Erdoğan, Nazmiye Erol   +7 more
core   +1 more source