Results 81 to 90 of about 2,588,152 (306)

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

Advanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching, Hinako Ichikawa, Aya Motoyoshi, Shin Tanaka, Liam Morrow, Satoshi Shirae, Noriko Sakai, Shohei Kitahata, Michiko Mandai, Kazuaki Kadonosono   +9 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Cell-based therapies for retinal degenerative diseases: A thousand strategies

, 2013
Retinal neuronal death causes a severe and irreversible loss of visual function in the patients of retinitis pigmentosa, agerelated macular degeneration and glaucoma, but these degenerative diseases currently still lack effective medical treatments.
Xie, Ting, Lewallen, Michelle
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Assessment of Relationship between Neovascularization Type Using Wide Field Optical Coherence Tomography Angiography in Eyes with Proliferative Diabetic Retinopathy

Ophthalmology and Therapy
Introduction Retinal neovascularization in proliferative diabetic retinopathy (PDR) presents with varying morphology and clinical implications. This study aims to classify retinal neovascularization into subtypes and assess their correlation with ...
Akshita Aggarwal, Dibya Prabha, Brijesh Takkar, Sobha Sivaprasad, Padmaja Kumari Rani   +4 more
doaj   +1 more source

Exudative Retinal Detachment

, 2016
Exudative retinal detachment refers to the separation of the neurosensory retina from the underlying retinal pigment epithelium (RPE) as a result of abnormalities of the normal hydrostatic/osmotic pressure gradients or transport mechanisms that maintain ...
Harry W. Flynn, Thomas A. Albini, Flynn, Harry W, Albini, Thomas A, Nidhi Relhan, Relhan, Nidhi   +5 more
core   +1 more source

Retinal arterioles narrow with increasing duration of anti-retroviral therapy in HIV infection: a novel estimator of vascular risk in HIV? [PDF]

, 2012
OBJECTIVES: HIV infection is associated with an increased risk of age-related morbidity mediated by immune dysfunction, atherosclerosis and inflammation.
Pathai, Sophia, Peto, Tunde; id_orcid, Tien Y Wong, Weiss, Helen A, Helen A Weiss, Colin Cook, Cook Colin, Tien Y. Wong, Tunde Peto, Lawn, Stephen D, Gilbert Clare E., Weiss Helen A., Wong Tien Y., Stephen D Lawn, Leris M D'Costa, Clare E. Gilbert, Peto Tunde, Sophia Pathai, Pathai Sophia, Leris M. D’costa, Lawn Stephen D., Cook, Colin, Helen A. Weiss, D’Costa Leris M., Gilbert, Clare E, Stephen D. Lawn, Peto, Tunde, Wong, Tien Y, D'Costa, Leris M, Clare E Gilbert, Cook, C., Pathai, S., Peto, T., Weiss, H.A., Lawn, S.D., D'Costa, L.M., Gilbert, C.E., Wong, T.Y.   +37 more
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

The Influence of Retinal Eye Diseases on Painting [PDF]

, 2015
In this work the possible infl uences of some retinal eye problems on paintings of several famous artists are considered. The change of painting styles and artistic expression in different periods and ages in a group of world-wide well-known painters ...
Ivanišević, Petar, Ivanišević, Milan
core   +1 more source