Results 61 to 70 of about 2,469,822 (264)

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Kerstin N. Euler, Ueffing, Marius, Fröhlich, K.J.H., Stefanie Hauck, Marius Ueffing, Euler, K.N., Fröhlich, Kristina J. H., Kerstin Euler, Claudia Alge-priglinger, Stefanie M. Hauck, Deeg, Cornelia A., Hauck, Stefanie M., Kristina J. H. Fröhlich, Euler, Kerstin N., Cornelia A. Deeg, Christoph Szober, Szober, Christoph M., Hauck, S.M., Ueffing, M., Kristina Fröhlich, Cornelia Deeg, Christoph M. Szober, Szober, C.M., Alge-Priglinger, C.S., Alge-Priglinger, Claudia, Deeg, C.A.   +25 more
core   +1 more source

Retinal Oxygenation in Inherited Diseases of the Retina

, 2021
(1) Background: The aim of our study was to investigate the relationship between retinal metabolic alterations (retinal vessel oximetry, RO) and structural findings (retinal vessel diameter, central retinal thickness and retinal nerve fiber layer ...
Cengiz Türksever, Lisette T. López Torres, Christophe Valmaggia, Margarita G. Todorova   +3 more
core   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography [PDF]

, 2009
BACKGROUND: Optical coherence tomography (OCT) is a novel method of retinal in vivo imaging. In this study, we assessed the potential of OCT to yield histology-analogue sections in mouse models of retinal degeneration.
Gesine Huber, Huber, G., Muehlfriedel, Regine, Edda Fahl, Jan Wijnholds, Beck, SC, Remé Charlotte E., Tanimoto, Naoyuki, Tanimoto Naoyuki, Pacal, M, Van de Pavert, S.A., Fischer M. Dominik, Fischer, M.D., Pacal Marek, Christian Grimm, Muehlfriedel Regine, Wenzel, Andreas, Charlotte E Remé, Charlotte E. Remé, Pacal, Marek, Serge A van de Pavert, M. Dominik Fischer, Rod Bremner, Wenzel, A., Bremner Rod, Remé, Charlotte E, Fischer, M Dominik, Susanne C. Beck, Huber, Gesine, Wijnholds, J, Fahl, E, Beck, S.C., Marek Pacal, Grimm Christian, Wenzel, A, Regine Muehlfriedel, Huber Gesine, Wijnholds, Jan, Tanimoto, N, Bremner, R., Reme, C.E., Wijnholds, Jan; https://orcid.org/, Bremner, R, Seeliger Mathias W., Beck, Susanne C., Fischer, M. Dominik, Mathias W Seeliger, Wijnholds Jan, Bremner, Rod, van de Pavert Serge A., M Dominik Fischer, Andreas Wenzel, Mühlfriedel, Regine, Tanimoto, N., Fahl, E., Seeliger, Mathias W, Fischer, Manuel, Beck Susanne C., Seeliger, Mathias W., Remé, Charlotte E., Van De Pavert, SA, Fahl, Edda, Pacal, M., Remé, CE, van de Pavert, Serge A., Beck, Susanne C; https://orcid.org/, Huber, G, Grimm, C., Seeliger, MW, Wenzel Andreas, Fahl Edda, Mathias W. Seeliger, Pavert, S.A. van de, Grimm, C, Grimm, Christian, Grimm, Christian; https://orcid.org/, Muehlfriedel, R., Serge A. Van De Pavert¤b, Wijnholds, J., van de Pavert, Serge A, Susanne C Beck, Fischer, MD, Muehlfriedel, R, Seeliger, M.W., Naoyuki Tanimoto   +84 more
core   +2 more sources

Diagnosis of inherited retinal diseases

, 2021
Inherited retinal diseases are a frequent cause of severe visual impairment or blindness in children and adults of working age. Across this group of diseases, there is great variability in the degree of visual impairment, the impact on everyday life ...
Imran H. Yusuf, Charbel Issa, Peter, Johannes Birtel, Yusuf, Imran, Birtel, Johannes, Rudolph, Günter, Günter Rudolph, Priglinger, Claudia, Peter Charbel Issa, Claudia Priglinger   +9 more
core   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy

Scientific Reports, 2017
In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood.
Pierre-Raphaël Rothschild, Sawsen Salah, Marianne Berdugo, Emmanuelle Gélizé, Kimberley Delaunay, Marie-Christine Naud, Christophe Klein, Alexandre Moulin, Michèle Savoldelli, Ciara Bergin, Jean-Claude Jeanny, Laurent Jonet, Yvan Arsenijevic, Francine Behar-Cohen, Patricia Crisanti   +14 more
doaj   +1 more source

Peripheral Retinal Abnormalities

, 2016
Peripheral retinal abnormalities are common and usually not consequential, but might obfuscate patient ...
Smiddy, William E, William E. Smiddy, Campagnoli, Thalmon R, Thalmon R. Campagnoli   +3 more
core   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Retinal break and rhegmatogenous retinal detachment after transpupillary thermotherapy as primary or adjunct treatment of choroidal melanoma

, 2008
OBJECTIVE: To report the development of retinal break or rhegmatogenous retinal detachment (RRD) after transpupillary thermotherapy (TTT) as primary or adjunct treatment of choroidal melanoma. METHODS: In this noncomparative, interventional case series,
이성철
core   +1 more source