Results 71 to 80 of about 211,361 (268)

Associations between Individual Retinal Layer Thicknesses and Diabetic Peripheral Neuropathy Using Retinal Layer Segmentation Analysis.

, 2018
PURPOSE: To evaluate clinical correlations between the thicknesses of individual retinal layers in the foveal area of diabetic patients and the presence of diabetic peripheral neuropathy (DPN).
김성수, 김진형, 변석호, 이성철, 고형준, 김민, 이민우   +6 more
core   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

TOXICITY and RETINAL PENETRATION of INFLIXIMAB in PRIMATES

, 2012
Purpose: To evaluate the retinal penetration and toxicity of two doses of intravitreal infliximab in primates.Methods: Ten marmosets (Callithrix jacchus) were given intravitreal injection of 100 mu g or 400 mu g of infliximab, and balanced salt solution ...
Coimbra, Rita C. S. G. [UNIFESP], Haapalainen, Edna Freymuller [UNIFESP], Eduardo B Rodrigues, Marcelo M Pinheiro, Milton N Moraes Filho, Gustavo B Melo, Juliana L Dreyfuss, Regatieri, Caio V. [UNIFESP], Moraes Filho, Milton N. [UNIFESP], Rodrigues, Eduardo B. [UNIFESP], Edna F Haapalainen, Pinheiro, Marcelo M. [UNIFESP], Michel E Farah, Farah, Michel E. [UNIFESP], Rita C S G Coimbra, Caio V Regatieri, Dreyfuss, Juliana L. [UNIFESP], Penha, Fernando M. [UNIFESP], Fernando M Penha, Melo, Gustavo B. [UNIFESP]   +19 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Retinal imaging /

, 2006
Internationally recognized experts in retina, glaucoma, and imaging techniques provide a complete review of posterior segment imaging. It is brief enough to read as a primer on ophthalmic imaging, yet comprehensive enough to refer to when you encounter ...
Huang, David.
core  

Artificial intelligence and deep learning in retinal image analysis

, 2019
Publisher Copyright: © 2019 Elsevier Ltd. All rights reserved.Our goal in this chapter is to describe the recent application of deep learning and artificial intelligence (AI) techniques to retinal image analysis.
Burlina, Philippe, Cohen, Adam, Galdran, Adrian, Costa, Pedro, Campilho, Aurélio   +4 more
core   +1 more source

Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]

, 2012
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger, Yu, Alice L., Burger, Johannes, Welge-Lussen, Ulrich, Alice L Yu, Kerstin Birke, Birke, Kerstin, Alice L. Yu, Ulrich Welge-Lussen   +8 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Standardization of OCT Angiography Nomenclature in Retinal Vascular Diseases [PDF]

Objective: To develop a consensus nomenclature for OCT angiography (OCTA) findings in retinal vascular diseases (RVDs). Design: Expert consensus using standardized online surveys with modified Likert scale.
Pircher M, Munk MR, Faes L, Peto T, Fabiani, Claudia, Freund KB, Kashani AH, Curcio CA, Wang RK, International Retinal Imaging Society Research Group, Jaggi D, Sadda SR, Turgut F, Sun J, Tommaso, Bacci   +14 more
core   +1 more source