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Towards Retinal Ganglion Cell Regeneration
Regenerative Medicine, 2012Traumatic optic nerve injury and glaucoma are among the leading causes of incurable vision loss across the world. What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression of vision loss.
Huasong, Gao +7 more
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Peptides influence retinal ganglion cells
Neuroscience Letters, 1981Neurotensin, substance P and (D-Ala2, Met5)-enkephalinamide were iontophoresed onto ganglion cells of the amphibian retina. Substance P and neurotensin were found to be excitatory while (D-Ala2, Met5)-enkephalinamide suppressed all types of ganglion cells. These findings are consistent with a functional role for peptides in the vertebrate retina.
E, Dick, R F, Miller
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Hyperacuity in Cat Retinal Ganglion Cells
Science, 1986Cat X retinal ganglion cells that can resolve sine gratings of only 2.5 cycles per degree can nevertheless respond reliably to displacements of a grating of approximately 1 minute of arc. This is a form of hyperacuity comparable in magnitude to that seen in human vision.
R, Shapley, J, Victor
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Retinal Ganglion Cell Topography in Elasmobranchs
Brain, Behavior and Evolution, 2000Retinal wholemounts are used to examine the topographic distribution of retinal cells within the ganglion cell layer in a range of elasmobranchs from different depths. The retina is examined for regional specializations for acute vision in six species of selachians, <i>Galeocerdo cuvieri, Hemiscyllium ocellatum, Scyliorhinus canicula, Galeus ...
Bozzano, A, Collin, SP
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Cat retinal ganglion cell dendritic fields
Experimental Neurology, 1966Abstract Retinal ganglion cells of the cat were stained by the techniques of Golgi (silver) and Ehrlich (in vivo methylene blue). These neurohistological techniques presumably stain a few nerve cells completely, and hence allowed the study of the form of the dendritic expansion of the cat ganglion cells.
J E, Brown, D, Major
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Culture of rat retinal ganglion cells
Journal of Huazhong University of Science and Technology [Medical Sciences], 2011This study aimed to modify the mixed and purified culture of rat retinal ganglion cells (RGCs) in vitro. The retinae of 1-3 day old Sprague-Dawley (SD) rats were separated bluntly into two layers: inner layer and outer layer, under a surgical microscope. Retinal cells isolated from different layers (inner layer, outer layer and whole retinal tissue) by
Zhirong, Xu +4 more
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Feature Detection by Retinal Ganglion Cells
Annual Review of Vision Science, 2022Retinal circuits transform the pixel representation of photoreceptors into the feature representations of ganglion cells, whose axons transmit these representations to the brain. Functional, morphological, and transcriptomic surveys have identified more than 40 retinal ganglion cell (RGC) types in mice.
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1988
Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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Classification of turtle retinal ganglion cells
Journal of Neurophysiology, 19891. Receptive fields of 78 retinal ganglion cells were analyzed for their responses to moving and stationary lights that were presented under a variety of stimulus conditions. All cells were sensitive to moving stimuli, and their receptive fields often comprised excitatory and inhibitory sub-regions. 2.
A M, Granda, J E, Fulbrook
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Topography of pig retinal ganglion cells
Journal of Comparative Neurology, 2005AbstractIn the present work we analyzed the distribution of retinal ganglion cells (RGCs) in the pig retina. RGCs were retrogradely labeled in vivo by injecting Fluoro‐Gold into the optic nerve. RGC density and the distribution of RGCs in terms of soma size were analyzed. Different regions of the porcine retina were identified following analysis of the
Mónica, Garcá +3 more
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