Results 131 to 140 of about 68,022 (253)

Primary open‐angle glaucoma as a marker of upcoming Alzheimer's disease: A 20‐year Danish National Registry‐Based Study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate whether primary open‐angle glaucoma (POAG) is associated with an increased long‐term risk of developing Alzheimer's disease, given its shared neurodegenerative features. Methods A 20‐year longitudinal, registry‐based matched cohort study was conducted using Danish national health registries from 1998 to 2018. Individuals
Cecilia Kronvold, Signe Sperling, Sören Möller, Jakob Grauslund, Lonny Stokholm   +4 more
wiley   +1 more source

The Retinal Ganglion Cell Layer [PDF]

Neurology, 1964
  +4 more sources

Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice

Journal of Pharmacological Sciences, 2017
Glutamate excitotoxicity mediated by N-methyl-d-aspartate (NMDA) receptors is an important cause of retinal ganglion cell death in glaucoma. To elucidate whether apelin protects against retinal neuronal cell death, we examined protective effects of ...
Yuki Ishimaru, Akihide Sumino, Daiki Kajioka, Fumiya Shibagaki, Akiko Yamamuro, Yasuhiro Yoshioka, Sadaaki Maeda   +6 more
doaj   +1 more source

Retinal ganglion cell layer thickness and volume measured by OCT changes with age, sex, and axial length in a healthy population. [PDF]

BMC Ophthalmol, 2022
Al-Hawasi A, Lagali N.
europepmc   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Overexpressing neurogenic differentiation factor 1 in Müller cells improves retinal function after optic nerve crush injury in adult mice

Neural Regeneration Research
Optic nerve injury leads to axonal degeneration and the death of retinal ganglion cells, which ultimately causes vision loss. Notably, current treatments are limited.
Liting Zhong, Dashuang Yang, Xiu Han, Haiyang Cheng, Di Xu, Wen Li, Gong Chen, Ying Xu   +7 more
doaj   +1 more source

The Temporal Retinal Nerve Fiber Layer Thickness Is the Most Important Optical Coherence Tomography Estimate in Multiple Sclerosis

Frontiers in Neurology, 2017
BackgroundReduced peripapillary retinal nerve fiber layer (pRNFL) and combined ganglion cell and inner plexiform layer (GCIP) thicknesses as measured by optical coherence tomography (OCT) have been observed in multiple sclerosis (MS) patients.
Ulrika Birkeldh, Ali Manouchehrinia, Max Albert Hietala, Jan Hillert, Tomas Olsson, Fredrik Piehl, Ingrid Skelton Kockum, Lou Brundin, Ori Zahavi, Marika Wahlberg-Ramsay, Rune Brautaset, Maria Nilsson   +11 more
doaj   +1 more source

Prognostic factors of optical coherence tomography angiography in intermediate and advanced primary open‐angle glaucoma: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Conventional optical coherence tomography (OCT) has a floor effect in patients with severe visual field loss, such as seen in advanced primary open‐angle glaucoma (POAG). OCT angiography (OCTA) does not suffer from such a floor effect. However, which OCTA parameters are most useful for monitoring longitudinal progression is unclear.
Kamya Katarya, Victor A. de Vries, João Barbosa‐Breda, Luisa Sanchez Brea, Danilo Andrade De Jesus, Wishal D. Ramdas   +5 more
wiley   +1 more source

Retinal Ganglion Cell Layer Thinning Followed By Retinal Nerve Fiber Layer Thinning In Patients with Uveitis

Journal of Clinical & Experimental Immunology, 2016
In the model of experimentally induced ischemia- reperfusion injury, retinal ganglion cells (RGC) expressing the gene AP-1 result apoptosis. The inflammation mediators, such as TNF-α, IL-1β, etc. lead RGC to apoptosis, that may lead the thinning of the retinal ganglion cell layer (RGCL) followed by the optic nerve fiber layer (RNFL) thinning.
openaire   +1 more source

Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate changes in choroidal and retinal thickness before and during myopia control treatment with orthokeratology lenses (OKL) in myopic children. Methods This was a sub‐study of CONTROL and CONTROL2 studies. The present study was a 2‐year, prospective, single‐group interventional study consisting of a 6‐month pre‐treatment ...
P. O. Hansen, F. Møller, T. M. Jakobsen
wiley   +1 more source