Results 271 to 280 of about 4,628,424 (310)
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Feature Detection by Retinal Ganglion Cells
Annual Review of Vision Science, 2022Retinal circuits transform the pixel representation of photoreceptors into the feature representations of ganglion cells, whose axons transmit these representations to the brain. Functional, morphological, and transcriptomic surveys have identified more than 40 retinal ganglion cell (RGC) types in mice.
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Peptides influence retinal ganglion cells
Neuroscience Letters, 1981Neurotensin, substance P and (D-Ala2, Met5)-enkephalinamide were iontophoresed onto ganglion cells of the amphibian retina. Substance P and neurotensin were found to be excitatory while (D-Ala2, Met5)-enkephalinamide suppressed all types of ganglion cells. These findings are consistent with a functional role for peptides in the vertebrate retina.
E, Dick, R F, Miller
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Towards Retinal Ganglion Cell Regeneration
Regenerative Medicine, 2012Traumatic optic nerve injury and glaucoma are among the leading causes of incurable vision loss across the world. What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression of vision loss.
Huasong, Gao +7 more
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Retinal Ganglion Cell Axon Fractionation
2023Retinal ganglion cell (RGC) axon regeneration in mammals can be stimulated through gene knockouts, pharmacological agents, and biophysical stimulation. Here we present a fractionation method to isolate regenerating RGC axons for downstream analysis using immunomagnetic separation of cholera toxin subunit B (CTB)-bound RGC axons.
Sean D, Meehan, Sanjoy, Bhattacharya
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1988
Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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The responses of the retinal ganglion cells of the frog
Vision Research, 1975Abstract Three groupsofunitswere recorded from theretinaof Rana esculenta . These were: (a)Units which responded to a square wave modulated light stimulus and these were of three types: ON units, ON-OFF units and OFF units. Stimulus-response curves for both a stimulating central spot and an annulus were constructed and the effects of increasing ...
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'Refracting' a Single Retinal Ganglion Cell
Archives of Ophthalmology, 1971The response characteristics of retinal ganglion cells to focused and blurred imagery and three interdependent response criteria, measured at the ganglion cell level, are used for the neurophysiological estimate of refractive error.
R M, Hill, H, Ikeda
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Diacylglycerol Signaling in Retinal Ganglion Cells
With impaired retinal ganglion cell (RGC) function and eventual RGC death, there is a heightened risk of experiencing glaucoma-induced blindness or other optic neuropathies. Poor RGC efficiency leads to limited transmission of visual signals between the retina and the brain by RGC axons.Ishan, Chaplot +3 more
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Retinal Ganglion Cells and Neuroprotection for Glaucoma
Survey of Ophthalmology, 2003Neuroprotection is a therapeutic strategy directed at keeping retinal ganglion cells (RGCs) alive and functional. This article discusses three commonly asked questions about neuroprotection and attempts to answer them in the context of our current understanding of the pathophysiology of RGC loss in glaucomatous optic neuropathy.
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Concerted Signaling by Retinal Ganglion Cells
Science, 1995To analyze the rules that govern communication between eye and brain, visual responses were recorded from an intact salamander retina. Parallel observation of many retinal ganglion cells with a microelectrode array showed that nearby neurons often fired synchronously, with spike delays of less than 10 milliseconds.
M, Meister, L, Lagnado, D A, Baylor
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