Results 311 to 320 of about 286,988 (401)

Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types

The Journal of Physiology, EarlyView.
Abstract figure legend Photoreceptor loss has heterogeneous effects on functional retinal ganglion cell (RGC) types. A, illustrations of cross‐sections of rd10 retinae at different time points during degeneration. Left: P30, rod degeneration has commenced, cones are still unaffected.
Nadine Dyszkant, Jonathan Oesterle, Yongrong Qiu, Merle Harrer, Timm Schubert, Dominic Gonschorek, Thomas Euler   +6 more
wiley   +1 more source

Adaptations to hypoxia in the vertebrate retina

The Journal of Physiology, EarlyView.
Abstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Michael G. Jonz
wiley   +1 more source

The mysterious middlemen making your vision pop: understanding the function of amacrine cells

The Journal of Physiology, EarlyView.
Abstract figure legend This review aims to illustrate the diversity and function of amacrine cells in the retina. The diversity of amacrine cell subtypes is depicted based on morphology, stratification and neurotransmitter expression, along with their synaptic connectivity with bipolar and ganglion cells, emphasizing inhibitory and modulatory roles ...
Victor Calbiague‐Garcia, Deborah Varro, Thomas Buffet, Olivier Marre   +3 more
wiley   +1 more source

Loss of monocyte chemoattractant protein-1 reduced monocyte recruitment and preserved retinal ganglion cells in a mouse model of hypertensive glaucoma. [PDF]

Exp Eye Res
Guo M, Schwartz TD, Lawrence ECN, Lu J, Zhong A, Wu J, Sterling JK, Nikonov S, Dunaief JL, Cui QN.   +9 more
europepmc   +1 more source

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

Glia, Volume 73, Issue 7, Page 1398-1419, July 2025.
Main Points Astrocytes play an important role in glaucoma. These cells express Cx43 which can form gap junctions and hemichannels. This study shows Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation.
Khulan Batsuuri, Abduqodir H. Toychiev, Suresh Viswanathan, Stefanie G. Wohl, Miduturu Srinivas   +4 more
wiley   +1 more source

Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. [PDF]

Neuron
Tian F, Cheng Y, Zhou S, Wang Q, Monavarfeshani A, Gao K, Jiang W, Kawaguchi R, Wang Q, Tang M, Donahue R, Meng H, Zhang Y, Jacobi A, Yan W, Yin J, Cai X, Yang Z, Hegarty S, Stanicka J, Dmitriev P, Taub D, Zhu J, Woolf CJ, Sanes JR, Geschwind DH, He Z.   +26 more
europepmc   +2 more sources

Potassium‐Dependent Coupling of Retinal Astrocyte Light Response to Müller Glia

Glia, Volume 73, Issue 7, Page 1520-1534, July 2025.
Main Points Astrocytes depolarize to light ON and OFF like Müller glia. The astrocyte light response is due to potassium influx. Retinal macroglial current‐voltage responses exhibit rectification which changes with repeated stimulation. ABSTRACT Astrocytes throughout the central nervous system mediate a variety of functions to support proper tissue ...
Joseph Matthew Holden, Andrew M. Boal, Lauren Katie Wareham, David John Calkins   +3 more
wiley   +1 more source

The protective effects of betaxolol against glutamate neurotoxicity in cultured retinal ganglion cells

, 2000
Makoto Shinya, Hiromu K. Mishima, Keisuke Shoge, Satoshi Mukai, Kumatoshi Ishihara, Masashi Sasa   +5 more
openalex   +1 more source

Enhanced restoration of visual code after targeting ON bipolar cells compared with retinal ganglion cells with optogenetic therapy. [PDF]

Mol Ther
Rodgers J, Hughes S, Ebrahimi AS, Allen AE, Storchi R, Lindner M, Peirson SN, Badea TC, Hankins MW, Lucas RJ.   +9 more
europepmc   +1 more source

Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high‐quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom.
Deysha Ratnasingham, George Lawson, Harpreet Hyare, Sam Gurney, John Apps, Ian Reekie, Sucheta Vaidya, Carmen Soto, Kavitha Srivatsa, Jaroslaw Peregud‐Pogorzelski, Andrzej Brodkiewicz, Owase Jeelani, Mette Jorgensen, Sarita Depani, Darren Hargrave, Elwira Szychot   +15 more
wiley   +1 more source