Results 321 to 330 of about 288,568 (403)

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

British Journal of Pharmacology, Volume 182, Issue 14, Page 3178-3210, July 2025.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison, Clauda Abboud, Dayana Abboud, Abdulrasheed O. Abdulrahman, Ana‐Nicoleta Bondar, Julie Dam, Zafiroula Georgoussi, Jesús Giraldo, Anemari Horvat, Christos Karoussiotis, Alba Paz‐Castro, Miriam Scarpa, Hannes Schihada, Nicole Scholz, Bilge Güvenc Tuna, Nina Vardjan   +15 more
wiley   +1 more source

The protective effects of betaxolol against glutamate neurotoxicity in cultured retinal ganglion cells

, 2000
Makoto Shinya, Hiromu K. Mishima, Keisuke Shoge, Satoshi Mukai, Kumatoshi Ishihara, Masashi Sasa   +5 more
openalex   +1 more source

Standardized and Calibrated Light Stimuli via Head‐Mounted Displays for Investigating the Nonvisual Effects of Light

Journal of Pineal Research, Volume 77, Issue 4, July 2025.
ABSTRACT Light influences human physiology profoundly, affecting the circadian clock and suppressing the endogenous hormone melatonin. Experimental studies often employ either homogenous full‐field stimulation, or overhead illumination, which are hard to standardize across studies and laboratories.
Maydel Fernandez‐Alonso, Manuel Spitschan   +1 more
wiley   +1 more source

Loss of monocyte chemoattractant protein-1 reduced monocyte recruitment and preserved retinal ganglion cells in a mouse model of hypertensive glaucoma. [PDF]

Exp Eye Res
Guo M, Schwartz TD, Lawrence ECN, Lu J, Zhong A, Wu J, Sterling JK, Nikonov S, Dunaief JL, Cui QN.   +9 more
europepmc   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

Advanced Science, Volume 12, Issue 22, June 12, 2025.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang, Shukui Zhang, Huiyang Jia, Fen Ji, Jianwei Jiao   +4 more
wiley   +1 more source

Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. [PDF]

Neuron
Tian F, Cheng Y, Zhou S, Wang Q, Monavarfeshani A, Gao K, Jiang W, Kawaguchi R, Wang Q, Tang M, Donahue R, Meng H, Zhang Y, Jacobi A, Yan W, Yin J, Cai X, Yang Z, Hegarty S, Stanicka J, Dmitriev P, Taub D, Zhu J, Woolf CJ, Sanes JR, Geschwind DH, He Z.   +26 more
europepmc   +2 more sources

The Ath5 proneural genes function upstream of Brn3 POU domain transcription factor genes to promote retinal ganglion cell development

, 2001
Wei Liu, Zeqian Mo, Mengqing Xiang
openalex   +1 more source

A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel

Advanced Science, Volume 12, Issue 21, June 5, 2025.
An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu, Yandi Zhou, Shuang Yao, Ziyi Wang, Sihao Ye, Rubing Qi, Hai Hu, Keke Liu, Yabo Wu, Tom Lawson, Lu Yan, Yong Liu, Wencan Wu   +12 more
wiley   +1 more source

Enhanced restoration of visual code after targeting ON bipolar cells compared with retinal ganglion cells with optogenetic therapy. [PDF]

Mol Ther
Rodgers J, Hughes S, Ebrahimi AS, Allen AE, Storchi R, Lindner M, Peirson SN, Badea TC, Hankins MW, Lucas RJ.   +9 more
europepmc   +1 more source

Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao, Yulian Zhou, Qing He, Wen Wen, Peng Zhang   +4 more
wiley   +1 more source