Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study
Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon+3 more
wiley +1 more source
Characterizing Presumed Displaced Retinal Ganglion Cells in the Living Human Retina of Healthy and Glaucomatous Eyes. [PDF]
Marte ME+6 more
europepmc +1 more source
Netrin‐4 Modulates Corneal Wound Healing by Enhancing Corneal Epithelium and Nerve Regeneration
Netrin‐4, an axon guidance protein, induces corneal wound healing by having a dual action on corneal epithelium and nerves. In vitro, Netrin‐4 enhances epithelium healing and neuronal growth in trigeminal ganglia neurons. In vivo, Netrin‐4 accelerated corneal epithelium regeneration in a model of corneal injury in mice. The effect of Netrin‐4 on nerves
Cissy Xiao+4 more
wiley +1 more source
AAV dose-dependent transduction efficiency in retinal ganglion cells and functional efficacy of optogenetic vision restoration. [PDF]
Lu Q, Wright A, Pan ZH.
europepmc +1 more source
The effect of advancing age and intraocular pressure injury on retinal ganglion cell function and synaptic connectivity. While young mice modulate their synaptic input to recover retinal ganglion cell function following injury, older mice compensate by altering their action potential threshold and axon initial segment (AIS) length to increase intrinsic
Vicki Chrysostomou+9 more
wiley +1 more source
Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells. [PDF]
Hu Y+11 more
europepmc +1 more source
Efficacy and specificity of melanopsin reporters for retinal ganglion cells. [PDF]
Maloney R+4 more
europepmc +1 more source
Interleukin-4 protects retinal ganglion cells and promotes axon regeneration. [PDF]
Zuo Z+5 more
europepmc +1 more source
The retinal ganglion cells in metabolic syndrome
Pappelis, Konstantinos+5 more
openaire +2 more sources