Results 31 to 40 of about 1,633 (148)

Hamartomas of the Retina and Optic Disc

Türk Oftalmoloji Dergisi, 2022
Hamartomas are local malformation of cells that demonstrate abnormal proliferation in the area where they are normally present. Retinal and optic disc hamartomas include astrocytic hamartoma, congenital hypertrophy of the retinal pigment epithelium ...
Ibadulla Mirzayev, Ahmet Kaan Gündüz
doaj   +1 more source

Diagnostic accuracy of retinal optical coherence tomography in children with a newly diagnosed brain tumour

Acta Ophthalmologica, Volume 101, Issue 6, Page 658-669, September 2023., 2023
Abstract Purpose To estimate the diagnostic accuracy of circumpapillary retinal nerve fibre layer (RNFL) thickness and macular ganglion cell layer–inner plexiform layer (GCL‐IPL) thickness measurements to discriminate an abnormal visual function (i.e. abnormal age‐based visual acuity and/or visual field defect) in children with a newly diagnosed brain ...
Myrthe A. Nuijts, Inge Stegeman, Giorgio L. Porro, Carlien A. M. Bennebroek, Tom van Seeters, Frank A. Proudlock, Antoinette Y. N. Schouten – van Meeteren, Saskia M. Imhof   +7 more
wiley   +1 more source

Primary cilia: Structure, dynamics, and roles in cancer cells and tumor microenvironment

Journal of Cellular Physiology, Volume 238, Issue 8, Page 1788-1807, August 2023., 2023
Primary cilium consists of the microtubule‐based axoneme as the main and scaffold structure, enclosed by a lateral ciliary membrane. A large number of receptors involving signal transduction such as Hedgehog (HH), Wnt, and Notch exist on the ciliary membrane for signal transduction. These primary cilium‐mediated signaling pathways are critical for cell
Yi‐Ting Guan, Chong Zhang, Hong‐Yong Zhang, Wen‐Lu Wei, Wei Yue, Wei Zhao, Dong‐Hui Zhang   +6 more
wiley   +1 more source

Comprehensive characterization and building of National Registry of von Hippel–Lindau disease in Brazil

Molecular Genetics &Genomic Medicine, Volume 11, Issue 4, April 2023., 2023
Von Hippel‐Lindau (VHL) is a hereditary syndrome that affects several visceral organs and the central nervous system. In this study, we report clinical and genetic characteristics of 142 participants with VHL. Therefore, we created the largest Brazilian cohort of VHL patients to define the main clinical characteristics and follow‐up of VHL disease, as ...
Tabatha Nakakogue Dallagnol, Eduardo Da Cás, Odery Ramos Junior, José Cláudio Casali‐da‐Rocha   +3 more
wiley   +1 more source

Peripheral retinal nonperfusion using widefield imaging with von Hippel-Lindau disease

International Journal of Retina and Vitreous, 2018
Background To describe a case of von Hippel-Lindau disease with peripheral retinal nonperfusion. Case presentation A 66-year-old female with known cerebellar and midbrain hemangioblastomas was evaluated for a retinal hemangioblastoma in the right eye ...
Jose S. Pulido, Lauren A. Dalvin, Timothy W. Olsen, Fukutaro Mano, Michael Yu, Carol L. Shields   +5 more
doaj   +1 more source

THERAPEUTIC OUTCOMES OF RETINAL HEMANGIOBLASTOMAS

Retina, 2014
To report the results of treatments and therapeutic complications of retinal hemangioblastomas (RH).Retrospective consecutive case series. Data from 32 patients (37 eyes) with RH were reviewed for characteristics of RH and treatment outcomes.Among 32 patients, we identified 73 RHs in 37 eyes.
Hyesun, Kim, Jeong H, Yi, Hee J, Kwon, Christopher S, Lee, Sung C, Lee   +4 more
openaire   +3 more sources

Treatment of juxtapapillary hemangioblastoma by intra-arterial (ophthalmic artery) chemotherapy with bevacizumab

American Journal of Ophthalmology Case Reports, 2018
Purpose: To report on two cases of treatment-refractory juxtapapillary hemagioblastomas that were managed with intra-arterial bevacizumab delivered via the ophthalmic artery.
Jasmine H. Francis, Jason S. Slakter, David H. Abramson, Steven A. Odrich, Y. Pierre Gobin   +4 more
doaj   +1 more source

Submacular sclerosing capillary hemangioblastoma

American Journal of Ophthalmology Case Reports, 2018
Purpose: To report a case of submacular cystic lesion that turned out to be a sclerosing capillary hemangioblastoma. The retinal capillary hemangioblastoma may arise as a part of von Hippel-Lindau syndrome 1 however, they may occur as an isolated entity ...
Hany S. Hamza, Abdelrahman M. Elhusseiny
doaj   +1 more source

Review of spectral domain-enhanced depth imaging optical coherence tomography of tumors of the retina and retinal pigment epithelium in children and adults

Indian Journal of Ophthalmology, 2015
Background: Spectral domain (SD) enhanced depth imaging optical coherence tomography (EDI-OCT) is a useful tool for anatomic, cross-sectional imaging of retinal conditions.
Carol L Shields, Janet Manalac, Chandana Das, Jarin Saktanasate, Jerry A Shields   +4 more
doaj   +1 more source

Effect of intravitreal dexamethasone on macular edema in von Hippel-Lindau disease assessed using swept-source optical coherence tomography: a case report

Journal of Medical Case Reports, 2018
Background Von Hippel-Lindau disease is a rare hereditary syndrome caused by germinal mutations in a von Hippel-Lindau tumor-suppressing gene. Retinal hemangioblastoma is the ocular hallmark lesion of von Hippel-Lindau disease.
Angelo Maria Minnella, Valeria Pagliei, Martina Maceroni, Matteo Federici, Gloria Gambini, Aldo Caporossi   +5 more
doaj   +1 more source