Results 51 to 60 of about 1,633 (148)

Pediatric patients with von Hippel–Lindau and hemangioblastomas treated successfully with belzutifan

Pediatric Blood &Cancer, Volume 72, Issue 1, January 2025.
Abstract Hemangioblastoma is the most common tumor associated with von Hippel–Lindau (VHL), and are a leading cause of mortality. We present five pediatric patients with VHL‐associated hemangioblastomas treated with belzutifan, a hypoxia‐inducible factor 2a (HIF2a) inhibitor. Three patients were started on belzutifan due to vision loss from progressive
Emily Duan, Michael Robinson, Charles Davis, Sumit Pruthi, Christina Shin, Marisa Lewis, Julian A. Martinez‐Agosto, Michael B. Gorin, Brian M. Shuch, Debra L. Friedman, Vivian Y. Chang   +10 more
wiley   +1 more source

Retinal vascular proliferation with fibrotic regression in von Hippel–Lindau disease

Taiwan Journal of Ophthalmology
In this study, we report a rare case of retinal vascular proliferation (RVP) in von Hippel–Lindau (VHL) disease, followed by a literature review. A 12-year-old boy presented with a left cerebellar hemangioblastoma and right eye blurred vision for 1–2 ...
Jing-Yi Chen, Hung-Da Chou, An-Ning Chao, Chi-Chun Lai, Mandeep S. Sagoo   +4 more
doaj   +1 more source

Juxtapapillary Hemangioblastoma: Case Report and Review of Literature

Delhi Journal of Ophthalmology, 2014
Purpose: To report a case of retinal vascular tumor and to review literature pertaining to management of retinal vascular tumors of the eye. Methods: Clinical data including medical history, findings on physical examination, local examination, Fundus ...
Anurag Narula, BP Guliani, HS Sethi, Pratyush Ranjan, Aniket Shastri, Vishnu Gupta   +5 more
doaj   +1 more source

Clinical and Genetic Characteristics of Retinal Capillary Hemangioblastoma in Korean Patients

Korean Journal of Ophthalmology, 2022
Purpose: We investigated the clinical features of Korean patients with retinal capillary hemangioblastoma (RCH) and genetic variants of the von Hippel-Lindau (<i>VHL</i>) gene.Methods: A retrospective analysis was performed on patients with RCH from 2003 to 2021 at Seoul National University Bundang Hospital.
Lee, Sang Ha, Park, Kyu Hyung, Woo, Se Joon, Park, Sang Jun, Joo, Kwangsic   +4 more
openaire   +2 more sources

Hemangioblastoma Instead of Renal Cell Carcinoma Plays a Major Role in the Unfavorable Overall Survival of Von Hippel-Lindau Disease Patients

Frontiers in Oncology, 2019
Von Hippel-Lindau (VHL) disease is a hereditary cancer syndrome characterized by poor survival. The effect of the involvement of each organ on survival remains unclear.
Bowen Zhou, Bowen Zhou, Bowen Zhou, Bowen Zhou, Jiangyi Wang, Jiangyi Wang, Shengjie Liu, Shengjie Liu, Shengjie Liu, Xiang Peng, Xiang Peng, Xiang Peng, Xiang Peng, Baoan Hong, Baoan Hong, Baoan Hong, Jingcheng Zhou, Jingcheng Zhou, Jingcheng Zhou, Kaifang Ma, Kaifang Ma, Kaifang Ma, Jiufeng Zhang, Jiufeng Zhang, Jiufeng Zhang, Lin Cai, Lin Cai, Lin Cai, Kan Gong, Kan Gong, Kan Gong   +30 more
doaj   +1 more source

The evolving landscape of tissue‐agnostic therapies in precision oncology

CA: A Cancer Journal for Clinicians, Volume 74, Issue 5, Page 433-452, September/October 2024.
ABSTRACT Tumor‐agnostic therapies represent a paradigm shift in oncology by altering the traditional means of characterizing tumors based on their origin or location. Instead, they zero in on specific genetic anomalies responsible for fueling malignant growth.
Vivek Subbiah, Mohamed A. Gouda, Bettina Ryll, Howard A. Burris III, Razelle Kurzrock   +4 more
wiley   +1 more source

Pancreatic Involvement in von Hippel Lindau Disease: A Single‐Center Experience

JGH Open, Volume 10, Issue 2, February 2026.
Ali Emre Bardak, Ceren Yazkac, Zulal Istemihan, Kanan Nuriyev, Asli Cifcibasi Ormeci, Bilger Cavus   +5 more
wiley   +1 more source

Successful endoscopic endonasal trans‐sphenoidal resection for pituitary macro adenoma with apoplexy in a twin pregnancy: A case report

Clinical Case Reports, Volume 12, Issue 7, July 2024.
Key Clinical Message Pituitary apoplexy is a medical and surgical emergency requiring prompt diagnosis and often urgent treatment to manage symptoms and prevent further complications. Abstract This report describes the successful management of a 37‐year‐old pregnant woman with a history of pituitary macroadenoma and apoplexy during a twin pregnancy ...
Ujjwal Kumar Jha, Pragyan Basnet, Sunil Kumar Das   +2 more
wiley   +1 more source

Whole-Genome Landscape of Retinal Hemangioblastomas

Translational Vision Science & Technology
Retinal hemangioblastomas (RHs) are rare benign vascular tumors that present mostly as manifestations of Von Hippel-Lindau (VHL) syndrome. In contrast to other VHL syndrome-associated tumors, only a handful of molecular studies have been published on RHs.
Bals, Kiki, Hajjaj, Anass, van Overdam, Koen A., Veckeneer, Marc, de Graaf, Bianca M., Eussen, Bert, Brands, Tom, Oldenburg, Rogier A., Alves, Maria M., Verdijk, Robert M., de Klein, Annelies, Kiliç, Emine, Brosens, Erwin   +12 more
openaire   +4 more sources

Optical coherence tomography angiography in assessment of response to therapy in retinal capillary hemangioblastoma and diffuse choroidal hemangioma

Indian Journal of Ophthalmology, 2019
In this series, we discuss the role of optical coherence tomography angiography (OCTA) in assessing response to treatment in intraocular vascular tumors.
Pradeep Sagar, P Mahesh Shanmugam, Vinaya K Konana, Rajesh Ramanjulu, K C Divyansh Mishra, Sriram Simakurthy   +5 more
doaj   +1 more source