Results 101 to 110 of about 51,224 (252)

Tuberculous Endophthalmitis With Phthisis Bulbi: A Diagnostic Delay Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Tuberculous endophthalmitis should be prioritized in differential diagnosis for unexplained endophthalmitis in TB‐endemic regions; early systemic evaluation, timely pars plana vitrectomy, and adjunctive corticosteroids are crucial to prevent phthisis bulbi, though evidence for some interventions remains limited.
Yanchen Chen, Shengnan Li, Xin Chen, Ningpu Liu, Dongjing Liu   +4 more
wiley   +1 more source

A case of HIV encephalopathy with HIV cerebrospinal fluid escape, followed by second-generation integrase inhibitor resistance

International Journal of Infectious Diseases
The management of advanced HIV can be complicated by immune reconstitution inflammatory syndrome (IRIS) and cerebrospinal fluid (CSF) viral escape.
Wen Wang, Jun Yang, Ziqiu Wang, Ying Wen
doaj   +1 more source

Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR T Cell Recipients – PART 1: Risk Factors, Clinical Impact and Immune Response

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT Human cytomegalovirus (HCMV) is one of the most important opportunistic pathogens in immunocompromised individuals, including allogeneic haematopoietic stem cell transplant (allo‐HSCT) recipients. In allo‐HSCT, HCMV seropositivity of the recipient and donor is associated with inferior survival outcomes, and post‐transplant HCMV reactivation is
Danya Kaplan, Emily Blyth, Gaurav Sutrave, Michelle K. Yong, David J. Gottlieb, Allison Abendroth, Barry Slobedman, Lauren Stern   +7 more
wiley   +1 more source

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

Aging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu, Gang Ning, Mintao Jian, Ajian Peng, Haoyu Wang, Bonan Li, Xing Zhou   +6 more
wiley   +1 more source

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]

, 2018
Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura, Giusti, Pietro, Skaper, Stephen D., Zusso, Morena   +3 more
core   +2 more sources

Herpes Zoster and Post-Herpetic Neuralgia—Diagnosis, Treatment, and Vaccination Strategies

Pathogens
Introduction: Herpes zoster is caused by the reactivation of latent varicella infection within the sensory ganglia, caused by the varicella-zoster virus (VZV).
Delwyn Zhi Jie Lim, Hong Liang Tey, Brenda Mae Alferez Salada, Jolene Ee Ling Oon, Ee-Jin Darren Seah, Nisha Suyien Chandran, Jiun Yit Pan   +6 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Definitions of the phenotypic manifestations of sickle cell disease. [PDF]

, 2009
Sickle cell disease (SCD) is a pleiotropic genetic disorder of hemoglobin that has profound multiorgan effects. The low prevalence of SCD ( approximately 100,000/US) has limited progress in clinical, basic, and translational research.
Adams, Albers, Ataga, Ballas, Ballas, Ballas, Ballas, Barnett, Benjamin, Benjamin, Bhalla, Castro, Dampier, De Castro, Eichhorn, Emond, Frenette, Gill, Gladwin, Hatton, Hern��ndez, Kato, Kato, Kato, Kinney, Leikin, Lisbona, Maitre, Manci, Moser, Orringer, Pappo, Petz, Platt, Platt, Seeler, Serjeant, Sheehy, Solanki, Tomlinson, Vichinsky   +40 more
core   +2 more sources

Newly Diagnosed AIDS with Multiple Opportunistic Infections Despite a Recent Negative Rapid HIV Test [PDF]

, 2013
Background Human Immunodeficiency Virus (HIV) is a fairly prevalent disease in the United States, with an estimated 1 million persons infected with HIV-1.1 Despite a decrease in Acquired Immunodeficiency Syndrome (AIDS), the prevalence of HIV is ...
Daniel, MD, PhD, Rene, Short, MD, MPH, William, Vakil, MD, Soham   +2 more
core   +2 more sources

Acute Retinal Necrosis Syndrome: A case report

Journal of Institute of Medicine Nepal, 2003
The acute retinal necrosis (ARN) syndrome represents a specific pattern of clinical presentation for certain herpes virus infections in the posterior segment of the eye. First described in the Japanese literature in 1971 and termed Kirisawa uveitis, it has till today remained a visually devastating condition in most of the cases. A female adult patient
J. K Shrestha, N. Tsering
openaire   +1 more source