Results 31 to 40 of about 2,814,729 (248)

Fulminant bilateral acute retinal necrosis syndrome associated with viral encephalitis: A case report.

open access: yesExperimental and Therapeutic Medicine, 2016
Herpes simplex virus (HSV) is the most common cause of acute viral encephalitis. Acute retinal necrosis (ARN) is a rapidly progressing and potentially blinding eye disease that may be induced by HSV. The present case study reports the very rare case of a
Chun-Kui Zhou, Lijun Zhu, Shao-Kuan Fang
semanticscholar   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Association Between Prognosis of Acute Retinal Necrosis and Retinal Involvement

open access: yes, 2022
Objectives:The aims of this study were to describe the clinical presentation and treatment modalities of acute retinal necrosis (ARN) and to evaluate complications and clinical outcomes according to the extent of retinal involvement at initial ...
Emre Altınkurt   +6 more
core   +1 more source

Acute retinal necrosis syndrome – a case report [PDF]

open access: yes, 2018
U radu su prikazani dijagnostički postupci i liječenje bolesnice oboljele od akutne retinalne nekroze uzrokovane varicella zoster virusom. Unatoč dugotrajnom liječenju ishod liječenja bio je nepovoljan i bolesnica je ostala trajno slabovidna na bolesno ...
Jakopović, Mislav   +2 more
core   +1 more source

Unilateral recurrent acute retinal necrosis syndrome caused by cytomegalovirus in an immune-competent adult

open access: yes
PURPOSE. To report an immune-competent patient with unilateral recurrent acute retinal necrosis syndrome caused by cytomegalovirus, and to highlight the importance of diagnostic vitreous biopsy and specific antiviral therapy in this condition.
Snow M, Griffiths PG, Pandit R, Voros GM
core   +5 more sources

Viral encephalitis complicated by acute retinal necrosis syndrome: A case report.

open access: yesExperimental and Therapeutic Medicine, 2015
Acute retinal necrosis syndrome (ARN) is a viral infection characterized by focal retinal necrosis. Viral meningitis complicated by ARN is relatively rare.
Zhigang Liang   +4 more
semanticscholar   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

open access: yesAdvanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu   +12 more
wiley   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

open access: yesAnimal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Implications of a local overproduction of tumor necrosis factor-α in complex regional pain syndrome [PDF]

open access: yes, 2011
Objective. To review the implications of a local overproduction of tumor necrosis factor-α for the pathogenesis and treatment of complex regional pain syndrome. Background.
Walker, S., Drummond, P.D.
core  

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun   +4 more
wiley   +1 more source

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