Results 61 to 70 of about 17,444 (187)

Early identification of vascular cognitive impairment from a multimodal perspective: a combined diagnosis from targeted cognitive assessments, imaging biomarkers, and molecular fluid biomarkers to ecological behavioral characteristics

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song, Xiaoqun Liu, Tianrui Yu, Yuanyuan Xiang, Peijie Fu, Moxin Wu, Xiaoping Yin, Xiaorong Zhang, Zhiying Chen   +8 more
wiley   +1 more source

Herpes Zoster and Post-Herpetic Neuralgia—Diagnosis, Treatment, and Vaccination Strategies

Pathogens
Introduction: Herpes zoster is caused by the reactivation of latent varicella infection within the sensory ganglia, caused by the varicella-zoster virus (VZV).
Delwyn Zhi Jie Lim, Hong Liang Tey, Brenda Mae Alferez Salada, Jolene Ee Ling Oon, Ee-Jin Darren Seah, Nisha Suyien Chandran, Jiun Yit Pan   +6 more
doaj   +1 more source

Preoperative Avapritinib for Localized PDGFRA‐Mutant GIST: Marked Pathologic Response, but Limited Feasibility at Standard Dosing

Cancer Medicine, Volume 15, Issue 8, August 2026.
In this two‐center retrospective series of eight patients with localized PDGFRA‐mutant gastric GIST treated with preoperative avapritinib, therapy produced substantial antitumor activity, including tumor reduction in 7 of 8 patients and complete or near‐complete pathologic response in all resected patients.
Tannaz Ranjbarian, Mark Antkowiak, Shirley Sarno, Shumei Kato, Adam M. Burgoyne, Skye C. Mayo, Michael C. Heinrich, Paul T. Fanta, Jason K. Sicklick   +8 more
wiley   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal, Caden M. Fritson, Alexandra Seas, Heidi Vieira, Surinder K. Batra   +4 more
wiley   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal, Anuradha Bankar, Vinicio A. de Jesus Perez   +2 more
wiley   +1 more source

Acute Retinal Necrosis Syndrome: A case report

Journal of Institute of Medicine Nepal, 2003
The acute retinal necrosis (ARN) syndrome represents a specific pattern of clinical presentation for certain herpes virus infections in the posterior segment of the eye. First described in the Japanese literature in 1971 and termed Kirisawa uveitis, it has till today remained a visually devastating condition in most of the cases. A female adult patient
J. K Shrestha, N. Tsering
openaire   +1 more source

The Role of Immunoresolvents in Atherosclerosis: A Mini‐Review on Their Biology and Therapeutic Opportunities

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi, Alireza Nasirifar, Hoda Rahmani, Sara Falahi, Meysam Kashiri   +4 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Ocular manifestations of HIV infection/AIDS in South Indian patients

Indian Journal of Ophthalmology, 1999
Purpose: To evaluate the nature and prevalence of ocular manifestations in a group of patients with Human Immunodeficiency Virus (HIV) infection/Acquired Immunodeficiency Syndrome (AIDS) from South India, and to elaborate the impact of the disease on ...
Sahu Dinesh, Namperumalsamy P, Walimbe Prasad, Rajalakshmi Chitra   +3 more
doaj  

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source