Results 111 to 120 of about 614,157 (313)

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

Cytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah, Franz Meitinger, Midori Ohta   +2 more
wiley   +1 more source

Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy

ChemPlusChem, EarlyView.
Gold nanoparticles (AuNPs) are widely used in biomedicine, electronics, catalysis, and environmental science. Conventional synthesis relies on harsh chemicals, driving interest in eco‐friendly methods using plants, bacteria, fungi, and algae. Biomolecules like polyphenols, proteins, and fatty acids aid nanoparticle synthesis under mild conditions. This
Youfeng Yue, Akihiro Moriyama, Marie Mita, Yue Yu   +3 more
wiley   +1 more source

An objective function based technique for devignetting fundus imagery using MST

Informatics in Medicine Unlocked, 2019
Fundus photography is a powerful imaging modality that is utilized for detecting macular degeneration, retinal neoplasms, choroid disturbances, glaucoma and diabetic retinopathy.
Fousia M. Shamsudeen, G. Raju
doaj  

The use of lasers in veterinary ophthalmology: Recommendations based on literature: Laseranwendungen in der Veterinär-Ophthalmologie: Empfehlungen auf Basis der Literatur [PDF]

, 2017
Lasers are routinely used in veterinary ophthalmology for the treatment of a number of ophthalmic conditions and diseases. In veterinary ophthalmology, gas lasers (CO2 lasers) and semiconductor lasers (diode lasers) are used primarily, but the therapy of
Spiess, Bernhard M.
core  

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri, Ahmad Gharaibeh, Lubika Nkashama, Abdelrahman Abushouk, Osama Abushawer, Amir Mehdizadeh‐Shrifi, Bianca Honnekeri, Cassandra Calabrese, Venu Menon, Pauline Funchain, Patrick Collier, Diego Sadler, Rohit Moudgil   +12 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Systemic anti-CD20 (rituximab) as primary treatment for symptomatic primary uveal lymphoma

American Journal of Ophthalmology Case Reports, 2019
Purpose: Uveal lymphomas are indolent, frequently choroid-involving neoplasms that are mainly CD20-positive B-cell extranodal marginal zone lymphoma. Irreversible visual loss may occur from retinal detachment and/or glaucoma among untreated symptomatic ...
Honeylen Maryl Tiu Teo, Süleyman Çiftçi, Victor Maurice Elner, Hakan Demirci   +3 more
doaj  

Smart Healthcare: The Role of Digital Health in Modern Medicine

Health Care Science, EarlyView.
Implementation of Digital Health. Innovations in Digital Health. Challenges in Digital Health. ABSTRACT Digital health is transforming healthcare by integrating advanced technologies to make healthcare more accessible, efficient, and personalized. From electronic health records, telemedicine, wearable devices, and artificial intelligence to the recent ...
Nidha Shapoo, Naveed Shapoo, Abdul Rehman, Noella Boma   +3 more
wiley   +1 more source

Vision Changes After Head and Neck Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Background Literature about ocular toxicity after head and neck cancer (HNC) treatment is scarce. This study aimed to describe visual function and ocular symptoms among HNC patients. Methods The study used a cross‐sectional design. Two surveys, The National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and an Ocular Symptom Scale ...
Hsiao‐Lan Wang, Megan Heskett, Peng Li, Laura Dreer, David Vance, Susan McCammon, Kailei Yan, Amanda Elliott   +7 more
wiley   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source