Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat. [PDF]
, 2019 Diabetic retinopathy is the most common microvascular complication of diabetes and is a major cause of blindness, but an understanding of the pathogenesis of the disease has been hampered by a lack of accurate animal models. Here, we explore the dynamics
Blodi, Barbara A +10 more
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Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization [PDF]
, 2000 Katrina Spilsbury +4 more
openalex +1 more source
Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care
Acta Ophthalmologica, EarlyView.Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano +26 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem +5 more
wiley +1 more source
Intrachoroidal Neovascularization in Transgenic Mice Overexpressing Vascular Endothelial Growth Factor in the Retinal Pigment Epithelium [PDF]
, 2001 Catherine Schwesinger +11 more
openalex +1 more source
Retinal Vessel Traits and Age‐Related Eye Disease in the Canadian Longitudinal Study on Aging
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To cross‐sectionally and longitudinally examine whether retinal vessel traits are associated with glaucoma‐related outcomes (glaucoma, cup‐to‐disc ratio [CDR] and intraocular pressure [IOP]) and age‐related macular degeneration (AMD).
Alexis O'Neil +8 more
wiley +1 more source
Inducible nitric oxide synthase mediates the change from retinal to vitreal neovascularization in ischemic retinopathy [PDF]
, 2001 Florian Sennlaub +2 more
openalex +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To explore the prevalence of serious adverse events (SAEs) associated with retinal viral gene therapy and to examine trends influencing SAE occurrences in human gene therapy surgeries and pre‐clinical animal trials. Methods Literature review was performed to identify peer‐reviewed human and animal studies relevant to viral gene ...
Aubrey Berger +3 more
wiley +1 more source
Intravitreal VEGF and bFGF produce florid retinal neovascularization and hemorrhage in the rabbit [PDF]
, 2001 Carolyn Wong +4 more
openalex +1 more source
The FEBS Journal, EarlyView.Transplantation of stem cell‐derived photoreceptors in retinal repair. We summarize methods for differentiating stem cells and describe surgical techniques for transplanting photoreceptor precursors to restore visual function (A). The effectiveness of these techniques is assessed with behavioral (B) and in vitro assays (C) using mouse models that mimic
Darin Zerti +5 more
wiley +1 more source