Results 151 to 160 of about 370,441 (288)

Phenotyping of retinal neovascularization in ischemic retinal vein occlusion using wide field OCT angiography

open access: yesEye, 2020
Josef Huemer   +9 more
semanticscholar   +1 more source

Noninvasive Detection of Chorioretinal Hypoxia via Poly(lactic‐co‐glycolic acid) Nanoparticles Embedded with Purely Organic Phosphors

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 4, April 2025.
A flexible lipid–polymer hybrid core–shell nanoparticle system that exhibits organic room‐temperature phosphorescence nanoprobes for real‐time optical imaging of ischemia‐induced tissue hypoxia. These biocompatible nanoprobes are highly sensitive to oxygen quenching and can effectively identify chorioretinal tissue hypoxia in clinically relevant living
Jung‐Moo Heo   +5 more
wiley   +1 more source

Escherichia coli in the production of biopharmaceuticals

open access: yesBiotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 528-541, April 2025.
Abstract Escherichia coli has shouldered a massive workload with the discovery of recombinant DNA technology. A new era began in the biopharmaceutical industry with the production of insulin, the first recombinant protein, in E. coli and its use in treating diabetes. After insulin, many biopharmaceuticals produced from E. coli have been approved by the
İbrahim İncir, Özlem Kaplan
wiley   +1 more source

The Chicken Embryo: An Alternative Animal Model in Development, Disease and Pharmacological Treatment

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 2, April 2025.
ABSTRACT To examine various medications and substances, in vivo models such as rats and mice are routinely used. However, it is utterly desirable to reduce extensive amounts of animals for these experimental models, which are costly and time‐consuming.
Oykum Kaplan‐Arabaci   +2 more
wiley   +1 more source

Targeting Frequent Efferocytosis in Tumor Microenvironment is a New Direction for Cancer Treatment

open access: yesSmall Science, Volume 5, Issue 4, April 2025.
Phagocytosis of “apoptotic tumor cells”, known as efferocytosis, accelerates the formation of an immunosuppressive microenvironment, leading to the detriment of tumor therapy. Blocking this process represents one of the novel approaches for treating tumors.
Gangxing Zhu   +9 more
wiley   +1 more source

circSIRT2/miR‐542‐3p/VASH1 axis regulates endothelial‐to‐mesenchymal transition (EndMT) in subretinal fibrosis in age‐related macular degeneration models

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
circSIRT2 inhibited SRF by binding miR‐542‐3p, which stimulated the VASH1 expression and subsequently suppressed EndMT. The circSIRT2/miR‐542‐3p/VASH1 axis may serve as a promising therapeutic target for SRF in nAMD. Abstract Neovascular age‐related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading ...
Min Zhang   +8 more
wiley   +1 more source

Hereditary Vitreoretinopathies: Molecular Diagnosis, Clinical Presentation and Management

open access: yesClinical &Experimental Ophthalmology, Volume 53, Issue 3, Page 281-291, April 2025.
ABSTRACT Hereditary vitreoretinopathies (HVRs), also known as hereditary vitreoretinal degenerations comprise a heterogeneous group of inherited disorders of the retina and vitreous, collectively and variably characterised by vitreal abnormalities, such as fibrillary condensations, liquefaction or membranes, as well as peripheral retinal abnormalities,
Hashem H. Ghoraba   +2 more
wiley   +1 more source

Involvement of Protein Kinase CK2 in Angiogenesis and Retinal Neovascularization [PDF]

open access: green, 2004
Alexander V. Ljubimov   +5 more
openalex   +1 more source

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