Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque +9 more
wiley +1 more source
Intrachoroidal Neovascularization in Transgenic Mice Overexpressing Vascular Endothelial Growth Factor in the Retinal Pigment Epithelium [PDF]
Catherine Schwesinger +11 more
openalex +1 more source
Neovascular age‐related macular degeneration without drusen
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks +9 more
wiley +1 more source
Inducible nitric oxide synthase mediates the change from retinal to vitreal neovascularization in ischemic retinopathy [PDF]
Florian Sennlaub +2 more
openalex +1 more source
Abstract Purpose Pregnancy induces significant changes in the body, including increased peripheral and choroidal blood perfusion and an increased systemic corticosteroid level. Here, we systematically reviewed the evidence on pregnancy as a risk factor for developing central serous chorioretinopathy (CSC) and conducted a meta‐analysis to obtain a ...
Nathalie Skovgaard Eriksen +15 more
wiley +1 more source
Pericyte Expression of VEGF-A Minimally Impacts Ocular Vascular Development and Neovascularization
Pericytes produce vascular endothelial growth factor-A (VEGF-A; hereafter referred to as VEGF). VEGF inhibits pericyte proliferation and migration through enhanced VEGFR2 and PDGFRβ heterodimerization.
Yong-Seok Song +5 more
doaj +1 more source
Intravitreal VEGF and bFGF produce florid retinal neovascularization and hemorrhage in the rabbit [PDF]
Carolyn Wong +4 more
openalex +1 more source
Natriuretic Peptides and the Regulation of Retinal Neovascularization [PDF]
Burtenshaw, Denise, Cahill, Paul A.
openaire +5 more sources
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger +8 more
wiley +1 more source
Detection of retinal neovascularizations using 45 ° and 60 ° photographic fields with varying 45 ° fields simulated on a 60 ° photograph [PDF]
Gunvor von Wendt +2 more
openalex +1 more source

