Results 151 to 160 of about 625,953 (241)

Construction and Validation of a Long‐Term Visual Prognosis Prediction Model for Proliferative Diabetic Retinopathy After Vitrectomy Based on Machine Learning

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
This study developed and validated a machine learning‐based prognostic model for predicting long‐term visual outcomes after pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy. ABSTRACT Introduction This study aims to develop a machine‐learning‐based risk prediction model for a long‐term visual prognosis in patients with ...
Xiaolu Wang, Jinghua Shi, Yan Gao, Tiantian Li, Xuehong Han, Lixia Guo, Tingting Jia, Yan Wang   +7 more
wiley   +1 more source

The roles of macrophage migration inhibitory factor in retinal diseases

Neural Regeneration Research
Macrophage migration inhibitory factor (MIF), a multifunctional cytokine, is secreted by various cells and participates in inflammatory reactions, including innate and adaptive immunity. There are some evidences that MIF is involved in many vitreoretinal
Hongbing Zhang, Xianjiao Zhang, Hongsong Li, Bing Wang, Pei Chen, Jiamin Meng   +5 more
doaj   +1 more source

A Multicentre Study of Prevalence and Risk Factors of Diabetic Retinopathy in Children and Young People With Type 1 Diabetes in the United Kingdom

Diabetes, Obesity and Metabolism, EarlyView.
Darren J. C. Toh, Satish Hulikere, Rabia Mufti, Mary Masoud, Alison Timmis, Ellie Pearce, Pooja Sachdev, Iqra Zameer, Swathi Upadrasta, Ramneek Kaur Manku, Astha Soni, Sze May Ng   +11 more
wiley   +1 more source

A Review of Artificial Intelligence in Ophthalmology: Key Aspects, Challenges, and Future Directions

Eye &ENT Research, Volume 3, Issue 3, Page 125-154, September 2026.
ABSTRACT Artificial intelligence (AI) is increasingly reshaping ophthalmology because the specialty depends heavily on structured imaging, quantitative measurements, and repeatable diagnostic workflows. This review provides a clinically grounded and translationally oriented synthesis of AI in ophthalmology, covering methodological foundations ...
Partha Pratim Ray
wiley   +1 more source

MicroRNA-143 plays a protective role in ischemia-induced retinal neovascularization

, 2019
Retinal neovascularization is a severe complication of proliferative diabetic retinopathy. MicroRNAs (miRNAs) are master regulators of gene expression that play important roles in retinal neovascularization.
Bui, BV, Tu, L, Prea, SM, Singh, V, Li, F, Liu, G-S, He, Z, Wang, J-H, Hewitt, AW, van Wijngaarden, P, Chen, J, Riaz, M, Ling, D, Dusting, GJ   +13 more
core   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

MedComm, Volume 7, Issue 9, September 2026.
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley   +1 more source

Risk factors for the development of subretinal fluid in the fellow eyes of patients with chronic central serous chorioretinopathy

Acta Ophthalmologica, Volume 104, Issue 6, Page 666-673, September 2026.
Abstract Purpose To assess the risk of subretinal fluid (SRF) development in the fellow eye of chronic central serous chorioretinopathy (cCSC) patients with unilateral SRF at baseline. Methods Medical records of 334 presumed cCSC patients were retrospectively reviewed.
Helena M. A. Feenstra, Tahir Cakar, Joost Brinks, Camiel J. F. Boon, Elon H. C. van Dijk   +4 more
wiley   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 6, Page 674-681, September 2026.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source

The Cell-Matrix Interface: a Possible Target for Treating Retinal Vascular Related Pathologies

Journal of Ophthalmic & Vision Research, 2012
Retinal vasculature related pathologies account for a large proportion of global blindness. Choroidal neovascularization accompanying age-related macular degeneration is the largest cause of blindness in people over the age of 65 years, proliferative ...
Gopalan Gnanaguru, William J Brunken
doaj