Advanced Science, Volume 12, Issue 33, September 4, 2025.This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren +11 more
wiley +1 more source
The Cell-Matrix Interface: a Possible Target for Treating Retinal Vascular Related Pathologies
Journal of Ophthalmic & Vision Research, 2012 Retinal vasculature related pathologies account for a large proportion of global blindness. Choroidal neovascularization accompanying age-related macular degeneration is the largest cause of blindness in people over the age of 65 years, proliferative ...
Gopalan Gnanaguru, William J Brunken
doaj
523. Inhibition of Retinal Neovascularization by Intraocular Gene Delivery of Soluble VEGF Receptors [PDF]
, 2004 Anand Srivastava +3 more
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Transcriptional Comparison of Human and Murine Retinal Neovascularization. [PDF]
Invest Ophthalmol Vis Sci, 2023 Pauleikhoff L +7 more
europepmc +1 more source
Extrafoveal seafan neovascularization associated with unilateral Recurrent retinal capillary haemangiomas: a known association or a mere coincidence [PDF]
, 2004 I U Kundi, W H Woon
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Lipid hydroperoxide-induced corneal and retinal neovascularization in the rabbit
, 2000 Takako Ueda
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Retinal pigment epithelial tear following photodynamic therapy for choroidal neovascularization secondary to AMD [PDF]
, 2005 M. Goldstein +3 more
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RNA Modifications in Health and Disease
MedComm, Volume 6, Issue 9, September 2025.Changes in these components profoundly affect the m6A methylation process, leading to a range of physiological and pathological alterations. In recent years, research on the post‐translational modifications of these components has advanced, encompassing ubiquitination, phosphorylation, SUMOylation, O‐GlcNAcylation, and lactylation.
Shiqi Li +5 more
wiley +1 more source
AAV2-antiVEGFscFv gene therapy for retinal neovascularization. [PDF]
Mol Ther Methods Clin Dev, 2023 Han N, Xu X, Liu Y, Luo G.
europepmc +1 more source
Optical scattering, absorption, and polarization of healthy and neovascularized human retinal tissues [PDF]
, 2005 Dhiraj K. Sardar +3 more
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