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Hypoxia and Retinal Neovascularization

2008
For over 50 years, retinal hypoxia has been considered to be a major causative factor in the development of retinal neovascularization (NV), a condition associated with blindness and vision loss in a variety of retinopathies. Review of the existing literature and results of new experiments from our laboratory strongly suggest that the oxygen-based ...
openaire   +2 more sources

Automatic Segmentation of Retinal Layer in OCT Images With Choroidal Neovascularization

IEEE Transactions on Image Processing, 2018
Age-related macular degeneration is one of the main causes of blindness. However, the internal structures of retinas are complex and difficult to be recognized due to the occurrence of neovascularization. Traditional surface detection methods may fail in
Dehui Xiang   +6 more
semanticscholar   +1 more source

Retinal Neovascularization After Branch Retinal Arterial Obstruction

American Journal of Ophthalmology, 1987
We examined two eyes from two noninsulin-dependent diabetic patients that developed vitreous hemorrhage secondary to retinal neovascularization after branch retinal arterial obstruction. Although there was no ophthalmoscopic evidence of diabetic retinopathy, diabetes mellitus may have predisposed the retinas to a neovascular response, which was ...
Gary C. Brown, Marvin F. Kraushar
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Neovascularization Detection on Retinal Images

2017
Proliferative Diabetic Retinopathy (PDR) is characterized by the growth of new abnormal, thin blood vessels called neovascularzation that spread along the retinal surface. An automated computer aided diagnosis system needs to identify neovasculars for PDR screening. Retinal images are often noisy and poorly illuminated.
Sudeshna Sil Kar   +2 more
openaire   +2 more sources

Vascular Casts of Experimental Retinal Neovascularization

American Journal of Ophthalmology, 1981
Autotransplantation of skin fibroblasts into the vitreous cavity of the rabbit eye resulted in the formation of fibrous strands that rapidly vascularized. To study this neovascularization, we injected methylmethacrylate monomer via the common carotid artery and made plastic casts between three days and three months after transplantation. Budding of new
Yasuo Tano   +2 more
openaire   +3 more sources

Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome.

JAMA ophthalmology, 2018
Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome Poretti-Boltshauser syndrome (PBS) is caused by LAMA1 (laminin1) (OMIM 150320) mutations and manifests with neurologic and ocular ...
Elizabeth D. Marlow   +4 more
semanticscholar   +1 more source

Indirect Treatment of Peripheral Retinal Neovascularization

American Journal of Ophthalmology, 1982
Indirect (scatter) cryotherapy and photocoagulation treatments successfully obliterated peripheral neovascularization in patients with sickle cell retinopathy and talc retinopathy. Fifteen of 17 neovascular fronds in seven eyes of five patients were obliterated. This type of treatment is analogous to panretinal photocoagulation for diabetic retinopathy.
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Antiangiogenesis Effects of Endostatin in Retinal Neovascularization

Journal of Ocular Pharmacology and Therapeutics, 2013
Pathological retinal angiogenesis is a major cause of vision loss. Endostatin is a natural antiangiogenesis antitumor protein that is widely used in cancer studies. In this study, we investigated the efficacy and potential mechanisms of endostatin for the prevention of retinal neovascularization both in vitro and in vivo.Human umbilical vein ...
Ai-Yi Zhou   +5 more
openaire   +3 more sources

Coordinate Control of Retinal Neovascularization

1982
Angiogenesis refers to the development of new blood vessels. Such a development can occur as a response to either normal physiological events or abnormal pathological conditions. Examples of normal angiogenic processes include the vascular development which occurs during embryogenesis (Sabin, 1920; Wagner, 1980) and wound healing (Clark and Clark, 1932;
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Neovascularization of the Iris in Rhegmatogenous Retinal Detachment

American Journal of Ophthalmology, 1991
To identify conditions associated with neovascularization of the iris in rhegmatogenous retinal detachment, we examined 36 eyes with this disorder seen at our hospital between 1979 and 1990. Clinical courses of disease were divided into the following three groups: (1) neovascularization of the iris without a history of a vitreoretinal operation (four ...
Akira Hirose   +5 more
openaire   +3 more sources

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