Results 91 to 100 of about 138,851 (338)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models

Stem Cell Reports, 2017
Summary: Antibody-mediated rejection is characterized by donor-specific antibody produced by B cells. However, to our knowledge, B cell invasion and antibody in the inflamed retina after transplantation of retinal pigment epithelial (RPE) cells has not ...
Sunao Sugita, Kenichi Makabe, Shota Fujii, Yuko Iwasaki, Hiroyuki Kamao, Takashi Shiina, Kazumasa Ogasawara, Masayo Takahashi   +7 more
doaj   +1 more source

Stimulation of AMPK prevents degeneration of photoreceptors and the retinal pigment epithelium

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance In this paper, we show that stimulation of adenosine monophosphate-activated protein kinase (AMPK) by metformin is able to protect photoreceptors and the retinal pigmented epithelium (RPE) in three different mouse models of retinal ...
Lei Xu, Li Kong, Jian-gang Wang, J. Ash
semanticscholar   +1 more source

Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication

Chemistry – A European Journal, EarlyView.
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin, Xinan Huang, Voichita Mihali, Cornelia G. Palivan   +3 more
wiley   +1 more source

RETINAL PIGMENT EPITHELIUM CONDITION AFTER LASER AND ULTRASOUND PHACOFRAGMENTATION. ELECTRON MICROSCOPY IN EXPERIMENT. REPORT 1

Офтальмохирургия, 2015
Purpose. To perform a comparative evaluation of a macular retinal pigment epithelium condition after laser and ultrasound phacofragmentations in experiment.Material and method.
S. Y. Kopayev, V. G. Kopayeva, S. A. Borsenok, V. U. Alborova   +3 more
doaj  

Near-infrared fundus autoflorescence imaging in solar retinopathy

GMS Ophthalmology Cases, 2017
Solar retinopathy is a rare clinical entity caused by photochemical damage to the retinal pigment epithelium layer and photoreceptors of the fovea. Here we describe a case of a 33-year-old female patient diagnosed by near-infrared fundus autofluorescence
Czepita, Maciej, Machalińska, Anna, Czepita, Damian   +2 more
doaj   +1 more source

Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo. [PDF]

PLoS ONE, 2016
The accumulation of N-retinylidene-N-retinylethanolamine (A2E, a toxic by-product of the visual pigment cycle) in the retinal pigment epithelium (RPE) is a major cause of visual impairment in the elderly.
Valérie Fontaine, Elodie Monteiro, Elena Brazhnikova, Laëtitia Lesage, Christine Balducci, Louis Guibout, Laurence Feraille, Pierre-Paul Elena, José-Alain Sahel, Stanislas Veillet, René Lafont   +10 more
doaj   +1 more source

Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration. [PDF]

, 2016
PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human
Annett, Geralyn, Cary, Whitney, Moisseiev, Elad, Motta, Monica, Murphy, Christopher J, Nolta, Jan A, Oltjen, Sharon, Park, Susanna S, Smit-McBride, Zeljka, Zawadzki, Robert J, Zhang, Pengfei   +10 more
core   +2 more sources

Phagocytosis-dependent ketogenesis in retinal pigment epithelium

Journal of Biological Chemistry, 2017
Daily, the retinal pigment epithelium (RPE) ingests a bolus of lipid and protein in the form of phagocytized photoreceptor outer segments (OS). The RPE, like the liver, expresses enzymes required for fatty acid oxidation and ketogenesis.
Juan Reyes-Reveles, A. Dhingra, Desiree Alexander, A. Bragin, N. Philp, K. Boesze-Battaglia   +5 more
semanticscholar   +1 more source

A comprehensive embryonic staging series of the turtle Trachemys scripta

Developmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian, Perla G. Rand, Amira Mahomed, Annie Rickard, Oscar D. Juvera, Maria Elena de Bellard, Max Ezin   +6 more
wiley   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David, Geurs, Sarah, Naert, Thomas, Sanders, Ellen, Tran Thi, Hong, Van Imschoot, Griet, Van Nieuwenhuysen, Tom, Van Roy, Frans, Vleminckx, Kris   +8 more
core   +3 more sources