Results 201 to 210 of about 138,851 (338)

Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors

Redox Biology, 2019
Emily E. Brown, Alexander J. DeWeerd, Cristhian J. Ildefonso, A. Lewin, J. Ash   +4 more
semanticscholar   +1 more source

Tocotrienols: A Review From Source to Therapeutic Applications

Food Frontiers, Volume 7, Issue 2, March 2026.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño, Nidia Casas‐Forero, Andres‐Felipe Garzón‐Méndez, Dalí‐Aleixandra Rojas‐Díaz, Mary‐Luz Olivares‐Tenorio, Hernan‐Mauricio Romero, Jesús‐Alberto García‐Núñez   +6 more
wiley   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Concentric retinal pigment epithelium tear in central serous chorioretinopathy

Indian Journal of Ophthalmology, 2019
Darshana Daga, Vinod Kumar, Shorya V Azad   +2 more
doaj   +1 more source

iPLA2β Protects Retinal Pigment Epithelium From Ferroptosis in a Sodium Iodate-Induced Model of Dry AMD. [PDF]

Invest Ophthalmol Vis Sci
Suzuki T, Terao R, Nagahara M, Hayashi K, Azuma K, Shinzawa K, Moriwaki K, Shiraya T, Honjo M, Ueta T.   +9 more
europepmc   +1 more source

ClC‐2 Contributes to Hypotonicity‐Induced Adrenal Aldosterone Secretion

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The zona glomerulosa (ZG) of the adrenal cortex regulates blood pressure and electrolyte homeostasis through aldosterone production. In ZG cells, potassium and angiotensin II (Ang II) trigger calcium oscillations that drive aldosterone synthesis.
Marina Volkert, Hoang An Dinh, Ute I. Scholl, Gabriel Stölting   +3 more
wiley   +1 more source

Prominin-1 Regulates Retinal Pigment Epithelium Homeostasis: Transcriptomic Insights into Degenerative Mechanisms. [PDF]

Int J Mol Sci
Huo W, Yin J, Ghose P, Schafer JC, Chaum E, Bhattacharya S.   +5 more
europepmc   +1 more source

Specialised features of melanosomes in health and disease in the retinal pigment epithelium. [PDF]

Front Cell Dev Biol
Doncheva D, Eden ER, Futter CE.
europepmc   +1 more source

Retinal pigment epithelium in the pathogenesis of age‐related macular degeneration and photobiomodulation as a potential therapy?

Clinical and Experimental Ophthalmology, 2018
J. Ao, J. Wood, G. Chidlow, M. Gillies, R. Casson   +4 more
semanticscholar   +1 more source

Evaluating VEGFR2 as a Target for Anti‐Tumour Therapy in Canine Melanoma

Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 95-104, March 2026.
ABSTRACT Vascular endothelial growth factor receptor 2 (VEGFR2) is a key target for anti‐angiogenic oncotherapy, as inhibiting this receptor on tumour vasculature slows tumour development and enhances drug‐ and immune infiltration, improving therapy outcome.
Esther Hindriks, Wilhelmina Bergmann, Aitor Martínez Ruiz, Maurice M. J. M. Zandvliet, Alice J. A. M. Sijts, Femke Broere   +5 more
wiley   +1 more source