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The retinal pigment epithelium in visual function.

Physiological Reviews, 2005
Located between vessels of the choriocapillaris and light-sensitive outer segments of the photoreceptors, the retinal pigment epithelium (RPE) closely interacts with photoreceptors in the maintenance of visual function. Increasing knowledge of the multiple functions performed by the RPE improved the understanding of many diseases leading to blindness ...
O. Strauß
semanticscholar   +4 more sources

Pigmented Lesions of the Retinal Pigment Epithelium

Optometry and Vision Science, 2015
: The primary eye care practitioner assumes an important role in clinical decisions involving the differentiation between malignant and nonmalignant pigmented lesions. A misdiagnosis may have profound consequences on patient management and visual or life prognosis.
Michael P Hennessy   +3 more
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Microrips of the Retinal Pigment Epithelium

Archives of Ophthalmology, 1992
We describe six patients with exudative age-related macular degeneration who had retinal pigment epithelial detachments with associated overlying neurosensory detachments. During fluorescein angiography, each patient demonstrated a solitary, intense, central serouslike leak at the edge of the retinal pigment epithelial detachment with passage of ...
Mark S. Blumenkranz   +5 more
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The Retinal Pigment Epithelium

Archives of Ophthalmology, 1982
The Retinal Pigmented Epithelium edited by Zinn and Marmor is well organized, clearly written, and beautifully illustrated. This scholarly work contains 26 chapters written by distinguished scientists and clinicians. Many have devoted a substantial portion of their careers to the study of the retinal pigment epithelium (RPE).
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Adenocarcinoma of the Retinal Pigment Epithelium

Archives of Ophthalmology, 1978
A 57-year-old woman complaining of decreased vision for six months had a mass expanding the choroid inferonasally in the right eye. Clinical examination, ultrasonography, and fluorescein angiography were consistent with a malignant melanoma. The eye was enucleated and pathologic studies showed an adenocarcinoma of the retinal pigment epithelium (RPE ...
Don S. Minckler, Arthur W. Allen
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Renaissance of the Retinal Pigment Epithelium

Archives of Ophthalmology, 1972
THE APPLICATION of recent advances in laboratory methods to the study of individual intraocular structures has greatly enhanced our ability to evaluate their function in health and disease. Nowhere is this more apparent than in the investigation of the retinal pigment epithelium where the utilization of light and electron microscopy coupled with ...
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Retinal Pigment Epithelium

2006
Retinal pigment epithelium (RPE) arises from neuroectoderm and plays a key role in support of photoreceptor functions. Several degenerative eye diseases, such as macular degeneration or retinitis pigmentosa, are associated with impaired RPE function that may lead to photoreceptor loss and blindness. RPE derived from human embryonic stem (hES) cells can
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The Retinal Pigment Epithelium

2005
Abstract The retinal pigment epithelium (RPE) is a monolayer of cuboidal epithelial cells intercalated between the photoreceptors and the choriocapillaries. The human RPE incorporates some 3.5 million epithelial cells arranged in a regular hexagonal pattern.
Tongalp H. Tezel, Morten la Cour
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