Results 211 to 220 of about 91,639 (372)

Distribution of fodrin and .ALPHA.-actinin in the rat retinal pigment epithelium in vivo.

, 1989
Mika Nihira, Toyoshi Fujimoto, Yoshihito Honda, Kazuo Ogawa   +3 more
openalex   +2 more sources

Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization [PDF]

, 2000
Katrina Spilsbury, Kerryn L. Garrett, Wei-Yong Shen, Ian J. Constable, Piroska E. Rakoczy   +4 more
openalex   +1 more source

The retinal pigment epithelium

Tissue Barriers in Disease, Injury and Regeneration, 2021
R. Nagymihaly, Yaroslav Nemesh, T. Ardan, J. Motlík, J. Eidet, M. Moe, L. Bergersen, L. Lytvynchuk, G. Petrovski   +8 more
semanticscholar   +1 more source

Transcriptional Heterogeneity and Differential Response of Rod Photoreceptor Pathway Uncovered by Single‐Cell RNA Sequencing of the Aging Mouse Retina

Aging Cell, EarlyView.
Healthy aging is accompanied by transcriptional dysregulation in retinal cells, leading to alterations in key molecular pathways and cellular responses, with the scotopic pathway being particularly affected. We show that rod photoreceptors, essential for initiating scotopic (low‐light) vision, exhibit selective vulnerability to aging‐associated ...
Laura Campello, Matthew J. Brooks, Benjamin R. Fadl, Hyo Sub Choi, Soumitra Pal, Anand Swaroop   +5 more
wiley   +1 more source

The retinal pigment epithelium: a versatile partner in vision

, 1993
Dean Bok
openalex   +1 more source

Subthreshold (retinal pigment epithelium) photocoagulation in macular diseases: a pilot study [PDF]

, 2000
J. Roider
openalex   +1 more source

Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD‐Like Pathology in Mice

Aging Cell, EarlyView.
Our study reveals that overactivation of both mTOR complexes through mLST8 in RPE cells triggers AMD‐like pathology and cellular dysfunction. This finding highlights the critical role of balanced mTOR signaling in retinal health and suggests that targeting both complexes could be therapeutic for AMD treatment.
Olivia Chowdhury, Sridhar Bammidi, Pooja Gautam, Vishnu Suresh Babu, Haitao Liu, Peng Shang, Ying Xin, Emma Mahally, Mihir Nemani, Victoria Koontz, Kira Lathrop, Katarzyna M. Kedziora, Jonathan Franks, Ming Sun, Joshua W. Smith, Lauren R. DeVine, Robert N. Cole, Nadezda Stepicheva, Anastasia Strizhakova, Sreya Chattopadhyay, Stacey Hose, Jacob Samuel Zigler Jr., José‐Alain Sahel, Jiang Qian, Prasun Guha, James T. Handa, Sayan Ghosh, Debasish Sinha   +27 more
wiley   +1 more source

Liver‐directed drugs for transthyretin‐mediated amyloidosis

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 228-237, December 2022., 2022
Abstract Transthyretin‐mediated amyloidosis (ATTR) is a rare, under‐recognized, progressively debilitating, fatal disease caused by the aggregation and extracellular deposition of amyloid transthyretin (TTR) fibrils in multiple organs and tissues throughout the body.
Thomas H. Brannagan 3rd, John L. Berk, Julian D. Gillmore, Mathew S. Maurer, Márcia Waddington‐Cruz, Marianna Fontana, Ahmad Masri, Laura Obici, Michela Brambatti, Brenda F. Baker, Lisa A. Hannan, Gustavo Buchele, Nick J. Viney, Teresa Coelho, Jose Nativi‐Nicolau   +14 more
wiley   +1 more source

The Challenge of the Retinal Pigment Epithelium [PDF]

Proceedings of the Royal Society of Medicine, 1974
openaire   +3 more sources

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

, 1993
Christian Hamel, Ekaterini Tsilou, Bruce A. Pfeffer, John J. Hooks, Barbara Detrick, T. Michael Redmond   +5 more
openalex   +1 more source