Results 281 to 290 of about 91,639 (372)

Safety of an Intravitreal Bevacizumab Biosimilar (MVASI)

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Intravitreal bevacizumab has been used off‐label to treat multiple ocular conditions for almost two decades. Reference bevacizumab, Avastin, was discontinued in Australia in 2021. A bevacizumab biosimilar, MVASI, was approved by the Therapeutic Goods Administration for the treatment of metastatic cancer in 2020.
Hanru Wang, Bobak Bahrami, Sonia Huang, Marzieh Tahmasebi Sarvestani, Sudha Cugati, Stewart Lake, Weng Onn Chan, Devaraj Supramaniam, Matthew Little   +8 more
wiley   +1 more source

Derivation and Comparative Assessment of Retinal Pigment Epithelium from Human Embryonic Stem Cells Using Transcriptomics [PDF]

, 2004
Irina Klimanskaya, Jason Hipp, Kourous A. Rezai, Michael West, Anthony Atala, Robert Lanza   +5 more
openalex   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano, Alejandra de‐la‐Torre, Silvana Guerriero, Stefania Costi, Gaafar Ragab, Maria Pia Paroli, Emanuela Del Giudice, Luciana Breda, Saverio La Bella, Marco Cattalini, Maria Cristina Maggio, Alex Fonollosa, Ester Carreño, Maria Tarsia, Rosanna Dammacco, Soad Hashad, Antonio Vitale, Lampros Fotis, Stefano Gentileschi, Francesca Minoia, Germán Mejía‐Salgado, Halah Etayari, Paola Saboya‐Galindo, María Andrea Bernal‐Valencia, Adele Civino, Maria Sole Chimenti, Valeria Caggiano, Maria Francesca Gicchino, Jurgen Sota, Angela Mauro, Giuseppe Lopalco, Kalpana Babu Murthy, Mohamed Tharwat Hegazy, Vishali Gupta, Francesco La Torre, Rana Hussein Amin, Bruno Frediani, Gian Marco Tosi, Luca Cantarini, Claudia Fabiani, on behalf of the AIDA Network   +40 more
wiley   +1 more source

Correlation of Structure With Function: Future Utilities for Optical Coherence Tomography Angiography in Neuro‐Ophthalmology

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani, Sudha Cugati, Celia Chen   +2 more
wiley   +1 more source

Spontaneous bilateral giant tears of the retinal pigment epithelium [PDF]

, 2004
Naohiro Izumi
openalex   +1 more source

A Chemical Reprogramming Approach Efficiently Producing Human Retinal Pigment Epithelium Cells for Retinal Disease Therapies

Cell Proliferation, EarlyView.
In this study, we combined a recently reported chemical reprogramming method alongside a guided differentiation approach, introducing a chemically defined scheme for generating functional human retinal pigment epithelium cells from adipose tissue. ABSTRACT Human induced pluripotent stem cells (hiPSCs) represent a promising cell source for generating ...
Ke Zhang, Yanqiu Wang, Qi An, Hengjing Ji, Defu Wu, Xuri Li, Lingge Suo, Chun Zhang, Xuran Dong   +8 more
wiley   +1 more source

Gypenosides protect retinal pigment epithelium cells from oxidative stress [PDF]

, 2018
Alhasani, Reem Hasaballah, Biswas, Lincoln, He, Jian-Feng, Reilly, James, Shu, Xinhua, Tohari, Ali Mohammad, Zhou, Xinzhi   +6 more
core   +2 more sources

Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein

, 2003
Daniel Gibbs, Junko Kitamoto, David S. Williams   +2 more
openalex   +1 more source

Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
hESCsdel18q exhibit delayed and impaired anterior neuroectoderm induction, leading to deficient RPE specification. hESCsdel18q lines showed dysregulation of TGFβ signalling, and endogenous overactivation of activin/nodal/TGFβ in hESCsdel18q leads to improper anterior/posterior neuroectodermal fate commitments.
Yingnan Lei, Mai Chi Duong, Nuša Krivec, Charlotte Janssens, Marius Regin, Anfien Huyghebaert, Edouard Couvreu de Deckersberg, Karen Sermon, Diana Al Delbany, Claudia Spits   +9 more
wiley   +1 more source

Tetrahedral Framework Nucleic Acid‐Based Delivery of DJ‐1‐saRNA Prevent Retinal Ischaemia–Reperfusion Injury via Inhibiting Ferroptosis

Cell Proliferation, EarlyView.
Illustration of the preparation of tFNAs‐DJ‐1 saRNAs complex and its inhibitory effects on ferroptosis in R28 and retina. ABSTRACT Retinal ischaemia/reperfusion injury (RI/RI) is the primary pathophysiological mechanism underlying retinal ischaemic diseases, potentially resulting in significant and irreversible visual impairment.
Xianggui Zhang, Zhende Deng, Xiaoxiao Xu, Jingyi Zhu, Zhen Huang, Ya Ye, Jingying Liu, Delun Luo, Jinnan Liu, Ming Yan, Yanping Song   +10 more
wiley   +1 more source