Results 21 to 30 of about 91,639 (372)
Scaffolds for retinal pigment epithelial cell transplantation in age-related macular degeneration
Journal of Tissue Engineering, 2017 In several retinal degenerative diseases, including age-related macular degeneration, the retinal pigment epithelium, a highly functionalized cell monolayer, becomes dysfunctional.
Corina E White, Ronke M Olabisi
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Choroidal vasculature imaging with laser Doppler holography [PDF]
, 2021 The choroid is a highly vascularized tissues supplying the retinal pigment epithelium and photoreceptors. Its implication in retinal diseases is gaining increasing interest. However, investigating the anatomy and flow of the choroid remains challenging.
arxiv +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The retinal pigment epithelium and the choroid are complex tissues whose dysfunction can lead to irreversible visual loss. In this study, single-cell RNA sequencing of both of these tissues was performed to characterize gene expression ...
Andrew P. Voigt +8 more
semanticscholar +1 more source
Journal of Tissue Engineering, 2016 The retinal pigment epithelium is an important part of the vertebrate eye, particularly in studying the causes and possible treatment of age-related macular degeneration.
Aaron H Fronk, Elizabeth Vargis
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Anomalous angiogenesis in retina [PDF]
Biomedicines 9, 224 (2021), 2021 Age-related macular degeneration (AMD) may cause severe loss of vision or blindness particularly in elderly people. Exudative AMD is characterized by angiogenesis of blood vessels growing from underneath the macula, crossing the blood-retina barrier (that comprise Bruch's membrane, BM, and the retinal pigmentation epithelium RPE), leaking blood and ...
arxiv +1 more source
Science Translational Medicine, 2019 A retinal pigment epithelial patch derived from mutation-free pluripotent stem cells shows therapeutic effects in rats and pigs. A pipeline for retinal stem cell therapy Autologous induced pluripotent stem cell (iPSC)–derived retinal pigment epithelium ...
Ruchi Sharma +25 more
semanticscholar +1 more source
Basic and Clinical Neuroscience, 2021 Introduction: Neurosphere-free transdifferentiation of bone marrow stem cells into Retinal Pigment Epithelium (RPE) and Retinal Cells (RCs) in vitro could offer an exceptional opportunity to study cell replacement in degenerative eye diseases.
Hamid AboutalebKadkhodaeian +2 more
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Hamartomas of the Retina and Optic Disc
Türk Oftalmoloji Dergisi, 2022 Hamartomas are local malformation of cells that demonstrate abnormal proliferation in the area where they are normally present. Retinal and optic disc hamartomas include astrocytic hamartoma, congenital hypertrophy of the retinal pigment epithelium ...
Ibadulla Mirzayev, Ahmet Kaan Gündüz
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Setting Eyes on the Retinal Pigment Epithelium [PDF]
Frontiers in Cell and Developmental Biology, 2018 The neural component of the zebrafish eye derives from a small group of cells known as the eye/retinal field. These cells, positioned in the anterior neural plate, rearrange extensively and generate the optic vesicles (OVs). Each vesicle subsequently folds over itself to form the double-layered optic cup, from which the mature eye derives.
Tania Moreno-Marmol +4 more
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Adenocarcinoma of retinal pigment epithelium. [PDF]
British Journal of Ophthalmology, 1987 This report describes a 41-year-old man with an intraocular tumour misinterpreted clinically as choroidal melanoma. The fluorescein angiographic features were not fully characteristic of uveal malignancy, and indeed histopathology revealed the diagnosis of adenocarcinoma of the retinal pigment epithelium.
P Dhermy +5 more
openaire +3 more sources