Results 291 to 300 of about 91,639 (372)
Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells
Andrea Milenkovic+13 more
semanticscholar +1 more source
Cardiomyocytes with high m.3243A>G burden exhibited hypertrophic phenotype. Mitochondria dysfunction occurred and tended to become round in cardiomyocytes with high m.3243A>G burden. Mitochondria‐associated ER membrane (MAM) was disrupted in cardiomyocytes with high m.3243A>G burden.
Miao Yu+10 more
wiley +1 more source
Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium
Jingyu Yao+10 more
semanticscholar +1 more source
We generated immune‐tolerant mature hESC‐RPE cells by overexpressing PD‐L1. PD‐L1‐expressing hESC‐RPE grafts exhibited significantly higher survival, reduced apoptosis and enhanced visual protection in retinal degeneration models, which presents an alternative target to improve the efficiency of hESC‐RPE‐based therapy for AMD. ABSTRACT Immune rejection
Bowen Li+11 more
wiley +1 more source
Intelligent Manufacturing for Osteoarthritis Organoids
Overall schematic of intelligent manufacturing in osteoarthritis organoids. Broad overview of the article's structure, outlining the progression from fundamental joint anatomy and OA pathogenesis to organoid construction and, ultimately, to intelligent manufacturing and future prospects.
Xukun Lyu, Jian Wang, Jiacan Su
wiley +1 more source
The expression of YY2 was significantly elevated in diabetic retinopathy, and YY2 blocked the serine synthesis pathway in retinal epithelial cells by inhibiting the transcriptional expression of PHGDH, thereby inducing the progression of oxidative stress and ferroptosis in the cells.
Xiang Lei, Xiu Wang, Xinai Zhang
wiley +1 more source
In situ quantification of ribosome number by electron tomography
Abstract Ribosomes, discovered in 1955 by George Palade, were initially described as small cytoplasmic particles preferentially associated with the endoplasmic reticulum (ER). Over the years, extensive research has focused on both the structure and function of ribosomes.
Mounir El Hankouri+4 more
wiley +1 more source