Results 311 to 320 of about 91,639 (372)

CEP162: A critical regulator of ciliary transition zone assembly and its implications in ciliopathies

Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Abstract CEP162, a 162‐kDa centrosome protein, is a crucial centrosomal adapter, mediating cell differentiation and polarization. CEP162 maintains mitosis by dynamically stabilizing microtubules. CEP162 promotes the transition zone (TZ) assembly in the basal body through interaction with CEP131, CEP290, and axoneme microtubules as well as the distal ...
Jun Yin, Jialian Bai, Xiaochong He, Wenjuan He, Hongming Miao, Mengjie Zhang, Zhongying Yu, Bing Ni   +7 more
wiley   +1 more source

Portuguese Society of Ophthalmology and Portuguese Society of Human Genetics Joint Clinical Practice Guidelines for Genetic Testing in Inherited Retinal Dystrophies

Clinical Genetics, Volume 107, Issue 6, Page 600-611, June 2025.
This study provides clinical practice guidelines to streamline genetic testing for inherited retinal dystrophies (IRDs), underscoring the critical role of molecular diagnosis in enhancing patient care. These recommendations aim to elevate diagnostic accuracy, guide therapeutic decisions, and ultimately improve patient outcomes, marking a significant ...
João Pedro Marques, Célia Azevedo Soares, Ana Luísa Carvalho, Sérgio Estrela‐Silva, Luísa Coutinho Santos, Lina Ramos, Eduardo Silva   +6 more
wiley   +1 more source

Is central vision (and a fovea) needed for emmetropisation?

Ophthalmic and Physiological Optics, EarlyView.
Frank Schaeffel, Christine Wildsoet, Ranjay Chakraborty   +2 more
wiley   +1 more source

Obesity‐related early structural alterations in the retina detected by optical coherence tomography

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3262-3273, June 2025.
Abstract Aims This retrospective cross‐sectional study, using retinal spectral‐domain optical coherence tomography (SD‐OCT) scans, investigated obesity‐related structural alterations in the retina. Materials and Methods Ninety‐two eyes of 92 healthy asymptomatic participants were categorized into two groups based on body mass index (BMI) measurements ...
Maide Gözde İnam, Onur İnam, Doru Gucer, James Park, Yasseen Amellal, Tongalp H. Tezel, Gülgün Tezel   +6 more
wiley   +1 more source

Key lines of discovery in myopia research

Ophthalmic and Physiological Optics, EarlyView.
Frank Schaeffel, Jeremy A. Guggenheim, Richard A. Stone, Christine F. Wildsoet   +3 more
wiley   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, Volume 15, Issue 5, Page 793-809, May 2025.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Central Serous Chorioretinopathy Diagnosed by Emergency Practitioner‐Performed Ocular Point‐Of‐Care Ultrasonography

Australasian Journal of Ultrasound in Medicine, Volume 28, Issue 2, May 2025.
ABSTRACT Introduction Central serous chorioretinopathy (CSCR) is a common cause of acute, monocular vision loss amongst men aged 40–50 years. Diagnosis is typically multimodal, requiring advanced ophthalmic imaging. These techniques are not readily available in acute care settings.
Christian P. Pappas, Matthew Watson, Christopher Harrington, Katherine Masselos   +3 more
wiley   +1 more source

Commentary: Detailed Visual Cortical Responses Generated by Retinal Sheet Transplants in Rats With Severe Retinal Degeneration. [PDF]

, 2019
Beyeler, Michael
core  

Vascular Endothelial Growth Factors in Eye Diseases. Pathophysiology and New Therapeutic Strategies for Retinal and Choroideal Angiogenesis (Verisuonikasvutekijöiden merkitys silmäsairauksissa. Patofysiologiaa ja uusia hoitomenetelmiä verkkokalvon ja suonikalvon angiogeneettisiin sairauksiin) [PDF]

Kinnunen, Kati
core  

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The Retinal Pigment Epithelium in Visual Function

Physiological Reviews, 2005
Located between vessels of the choriocapillaris and light-sensitive outer segments of the photoreceptors, the retinal pigment epithelium (RPE) closely interacts with photoreceptors in the maintenance of visual function. Increasing knowledge of the multiple functions performed by the RPE improved the understanding of many diseases leading to blindness ...
O. Strauß
openaire   +4 more sources