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Progenitor cells and retinal angiogenesis
Angiogenesis, 2007Nothing more dramatically captures the imagination of the visually impaired patient or the ophthalmologist treating them than the possibility of rebuilding a damaged retina or vasculature with "stem cells." Stem cells (SC) have been isolated from adult tissues and represent a pool of cells that may serve to facilitate rescue/repair of damaged tissue ...
Martin, Friedlander +8 more
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Expression of olig2 in retinal progenitor cells
NeuroReport, 2006Olig2 is a basic helix-loop-helix transcription factor that is specifically expressed in oligodendrocyte precursors in the central nervous system. Owing to the absence of oligodendrocytes in the retina, however, the role of olig2 in retinal development remains unclear.
Kazuaki, Nakamura +3 more
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Rat retinal progenitor cells and a retinal pigment epithelial factor
Developmental Brain Research, 2001Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor.
H J, Sheedlo +3 more
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Retinal stem/progenitor properties of iris pigment epithelial cells
Developmental Biology, 2006 Neural stem cells/progenitors that give rise to neurons and glia have been identified in different regions of the brain, including the embryonic retina and ciliary epithelium of the adult eye.
Mitsuko Kosaka, Maki Asami, Hiroshi Ohta
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Membrane properties of retinal stem cells/progenitors
Progress in Retinal and Eye Research, 2005The membrane properties of cells help integrate extrinsic information relayed through growth factors, chemokines, extracellular matrix, gap junctions and neurotransmitters towards modulating cell-intrinsic properties, which in turn determine whether cells remain quiescent, proliferate, differentiate, establish contact with other cells or remove ...
Ani V, Das +5 more
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Retinal Progenitor Cells — Timing Is Everything
New England Journal of Medicine, 2007Permitting progenitor photoreceptor cells from donors to differentiate before transplanting them is key to their successful integration into the retina.
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Microscopic characterization of rat retinal progenitor cells
Brain Research, 2007A progenitor cell line was developed from a postnatal day 2 (P2) rat retina to study the effects of secreted proteins of the retinal pigment epithelium (RPE) on isolated retinal progenitor cells and markers for immature and differentiated retinal cells. Progenitor cells were cloned from a P2 explant grown in secreted proteins of cultured RPE cells.
Harold J, Sheedlo +3 more
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