Results 151 to 160 of about 614,351 (314)

Data_Sheet_1_Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration.XLSX

, 2018
Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential.
Wuhong Pei (665643), Jeff S. Mumm (189420), David T. White (5648471), Timothy S. Mulligan (4608187), Liyun Zhang (280172), Meera T. Saxena (189416), Noela Y. Lu (5648477), Sumitra Sengupta (361221), Jiang Qian (771), Arife Unal Eroglu (410566), Lisha Xu (3614771), Cathy Nie (5648474), Shawn M. Burgess (265141)   +12 more
core   +1 more source

Self-Organization of the Retina during Eye Development, Retinal Regeneration In Vivo, and in Retinal 3D Organoids In Vitro. [PDF]

Biomedicines, 2022
Grigoryan EN.
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Amino acid responses in solitary spiking cells during retinal regeneration in the adult newt, Cynops pyrrhogaster [PDF]

, 1995
筑波大学University of Tsukuba博士（理学）Doctor of Philosophy in ScienceAdult newt (Cynops pyrrhogaster) prossesses the ability to regenerate a new functional retina following complete removal of the original retina.
Chiba, Chikafumi, 34598, 千葉, 親文
core  

Pou2f2 enhances retinal ganglion cell survival and axon regeneration after optic nerve injury [PDF]

D. N. Stavropoulos, Chia-Chun Liu, Shining Wang, Chi-Yu Chen, Mishal Rao, Laman Mirzaliyeva, Hui-Chun Cheng, Ya-Ling Lin, Andrew M. Williams, Yuan Pan, Takaaki Kuwajima, Jeffrey Louis Goldberg, José‐Alain Sahel, Kun‐Che Chang   +13 more
openalex   +1 more source

Inflammation Regulates the Multi-Step Process of Retinal Regeneration in Zebrafish. [PDF]

Cells, 2021
Nagashima M, Hitchcock PF.
europepmc   +1 more source

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

Phytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng, Xuelian Yuan, Yawen Xie, Zhenni Xia, Zhaohui Guo, Xuesong Liu, Rong Li, Wenliang Wang   +7 more
wiley   +1 more source

Photoreceptor regeneration occurs normally in microglia-deficient irf8 mutant zebrafish following acute retinal damage

Microglia are resident immune cells in the central nervous system, including the retina that surveil the environment for damage and infection. Following retinal damage, microglia undergo morphological changes, migrate to the site of damage, and express ...
Dhwani Parsana, Bela Anand-Apte, Brian D. Perkins, Lana M. Pollock, Ping Song, Rupesh Singh   +5 more
core   +1 more source

Image_2_Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration.pdf

, 2018
Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential.
Wuhong Pei (665643), Jeff S. Mumm (189420), David T. White (5648471), Timothy S. Mulligan (4608187), Liyun Zhang (280172), Meera T. Saxena (189416), Noela Y. Lu (5648477), Sumitra Sengupta (361221), Jiang Qian (771), Arife Unal Eroglu (410566), Lisha Xu (3614771), Cathy Nie (5648474), Shawn M. Burgess (265141)   +12 more
core   +1 more source

Therapeutic effects of mesenchymal stem cells-derived extracellular vesicles' miRNAs on retinal regeneration: a review. [PDF]

Stem Cell Res Ther, 2021
Rajool Dezfuly A, Safaee A, Salehi H.
europepmc   +1 more source