Results 131 to 140 of about 614,351 (314)

Retinal binding during folding and assembly of the membrane protein bacteriorhodopsin

, 1996
The factors driving folding and assembly of integral membrane proteins are largely unknown. In order to determine the role that the retinal chromophore plays in assembly of bacteriorhodopsin, we have determined the kinetics and thermodynamics of retinal ...
Booth, Paula J., Flitsch, Sabine L, Farooq, A, Farooq, Amjad, Flitsch, Sabine L., Flitsch, SL, Booth, PJ, Booth, Paula J, Amjad Farooq, Paula J. Booth, Sabine L. Flitsch   +10 more
core   +1 more source

Post‐ovipositional staging series of the foveate, gold‐dust day gecko, Phelsuma laticauda (Gekkota: Squamata)

Developmental Dynamics, EarlyView.
Abstract Background Disorders affecting the fovea, a specialized pit in the human retina necessary for high acuity vision, represent a significant healthcare burden across the globe. Degenerative diseases (e.g., macular degeneration) and developmental conditions (e.g., albinism and aniridia) affecting the fovea can lead to irreversible, central vision ...
Andrew E. Wegerski, Aaron H. Griffing, Courtney E. Murr, Tony Gamble, Brian P. Brooks, Robert B. Hufnagel, Ashley M. Rasys   +6 more
wiley   +1 more source

Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer

Nature Communications
Individuals with retinal degenerative diseases struggle to restore vision due to the inability to regenerate retinal cells. Unlike cold-blooded vertebrates, mammals lack Müller glia (MG)-mediated retinal regeneration, indicating the limited regenerative ...
Eun Jung Lee, Museong Kim, Sooyeon Park, Ji Hyeon Shim, Hyun-Ju Cho, Jung Ah Park, Kihyun Park, Dongeun Lee, Jeong Hwan Kim, Haeun Jeong, Fumio Matsuzaki, Seon-Young Kim, Jaehoon Kim, Hanseul Yang, Jeong-Soo Lee, Jin Woo Kim   +15 more
doaj   +1 more source

Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration

FlexTech, EarlyView.
Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley   +1 more source

Hematological- and Neurological-Expressed Sequence 1 Gene Products in Progenitor Cells during Newt Retinal Development

Stem Cells International, 2012
Urodele amphibians such as Japanese common newts have a remarkable ability to regenerate their injured neural retina, even as adults. We found that hematological- and neurological-expressed sequence 1 (Hn1) gene was induced in depigmented retinal pigment
Tatsushi Goto, Fumio Tokunaga, Osamu Hisatomi   +2 more
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Optical Stimulation and Monitoring of the Peripheral Nervous System: Perspectives and Challenges Toward Clinical Translation

Laser &Photonics Reviews, EarlyView.
Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo, Sarassunta Ucci, Anna Aliberti, Patrizio Vaiano, Alessia La Rocca, Francesca Angelone, Silvia Pascarella, Pellegrino Lippiello, Maria Concetta Miniaci, Giuseppe Prisco, Michela Russo, Francesco Amato, Deyanira Contartese, Milena Fini, Gianluca Giavaresi, Lucia Martini, Francesco Rosa, Cosimo Gentile, Emanuele Gruppioni, Armando Ricciardi, Andrea Cusano   +20 more
wiley   +1 more source

Retinal regeneration with iPS cells – Clinical trials for retinal degenerative disorders

Japanese Journal of Clinical Immunology, 2015
Potential for re-programming cells has become widely accepted as a tool for obtaining transplantation materials. There has been great interest in cell-based therapies, including retinal transplants, because there is a reduced risk of immune rejection.
openaire   +3 more sources

Lens injury stimulates adult mouse retinal ganglion cell axon regeneration via both macrophage- and lens-derived factors

, 2005
In the present study the effects of lens injury on retinal ganglion cell axon/neurite re-growth were investigated in adult mice. In vivo, lens injury promoted successful regeneration of retinal ganglion cell axons past the optic nerve lesion site ...
Logan, Ann, Lorber, Barbara, Berry, Martin   +2 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source