Results 111 to 120 of about 614,351 (314)

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

RETINAL DISPLACEMENT AFTER RETINECTOMY IN COMPLEX MACULA-INVOLVING RECURRENT RHEGMATOGENOUS RETINAL DETACHMENT

open access: yes
Retinectomy, essential for treating complex rhegmatogenous retinal detachment, significantly risks retinal displacement, detectable through fundus autofluorescence.
Shaheen, Abdulla   +7 more
core   +1 more source

Engineering Intelligent iPSC Biomanufacturing: Integrating Robotic Automation, AI, and Process Control

open access: yesAdvanced Intelligent Systems, EarlyView.
This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee   +3 more
wiley   +1 more source

Cerebrospinal Fluid Cytokine Expression and Relationships With Neurological Measures in Virologically Controlled People With HIV

open access: yesAnnals of Neurology, EarlyView.
Objective Quantify cytokines in cerebrospinal fluid (CSF) of virologically suppressed people with HIV (PWH) and people without HIV (PWoH) and correlate these with neuroimaging, neuropsychometric (NP), and neurodegenerative measurements. Methods CSF samples were collected from virologically suppressed PWH and demographically matched PWoH under a natural
Jack Peterson   +13 more
wiley   +1 more source

R102W mutation in the RS1 gene responsible for retinoschisis and recurrent glaucoma

open access: yesInternational Journal of Ophthalmology, 2014
AIM: To identify the mutations in RS1 gene associated with typical phenotype of X-linked juvenile retinoschisis (XLRS) and a rare condition of concomitant glaucoma.METHODS: Complete ophthalmic examinations were performed in the proband.
Xiu-Feng Huang   +5 more
doaj   +1 more source

Spontaneous Retinal Activity Is Tonic and Does Not Drive Tectal Activity during Activity-Dependent Refinement in Regeneration

open access: yes, 2002
During development, waves of activity periodically spread across retina to produce correlated activity that is thought to drive activity-dependent ordering in optic fibers.
Ronald L. Meyer, Bradley J. Kolls
core   +1 more source

Understanding the spacing of placodes in the eye: A comparative study across age and species

open access: yesThe Anatomical Record, EarlyView.
Abstract The conjunctival placodes of the avian eye form in an intriguing and conserved sequence in a circular annulus around the cornea. These 13–16 placodes develop into papillae that are essential for inducing underlying intramembranous flat bones, known as scleral ossicles, which form an important part of the ocular skeleton.
Florence Joseph   +1 more
wiley   +1 more source

Characterization of Midkine-a Function During Retinal and Caudal Fin Regeneration in the Adult Zebrafish

open access: yes, 2018
Zebrafish possess the remarkable ability to regenerate multiple tissues and organs. Given that many genetic and cellular components of the zebrafish are conserved in humans, the zebrafish is an ideal model for studying tissue regeneration.
Ang, Nicholas
core   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

open access: yesBiotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga   +2 more
wiley   +1 more source

Retinal Injury, Growth Factors, and Cytokines Converge on β-Catenin and pStat3 Signaling to Stimulate Retina Regeneration

open access: yes, 2014
SummaryMüller glia (MG) in the zebrafish retina respond to retinal injury by generating multipotent progenitors for retinal repair. Here, we show that Insulin, Igf-1, and fibroblast growth factor (FGF) signaling components are necessary for retina ...
Anne Vojtek   +3 more
core   +1 more source

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