Results 191 to 200 of about 614,351 (314)

Circadian clock gates retinal regeneration by orchestrating Cxcl12-dependent immune coordination [PDF]

Xiangyu Li, Haibo Li, Lianxin Wu, Bowen Lu, 植汉坤, Yi Li, Qianyi Lu, Han Wang, Hui Xu   +8 more
openalex   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Retinal organoids: From research tools to regenerative transplants

Madalina Alexandru, James Williamson, J. Jackow   +2 more
openalex   +2 more sources

Stem Cell-Based Interventions for Retinal Ganglion Cell Protection and Regeneration in Glaucoma: A Review of Current Evidence and Future Directions [PDF]

Tony Yihao Chen, Martin Meng, Na Wu, Daqian Rong, Xinghuai Sun   +4 more
openalex   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Prolonged rod photoresponse and enhanced cone sensitivity in the transgenic mouse retina lacking arrestin and guanylate cyclase activating proteins

The Journal of Physiology, EarlyView.
Abstract figure legend Analyses from mutant mouse retinal explants gives invaluable insights of the photosignaling process in rod and cone photoreceptor cells. A, Illustration of retinal photovoltage recordings. A retinal explant (pink) is placed in a transparent device which has electrodes to monitor transretinal voltage (red and blue circles).
Shinya Sato, Rikard Frederiksen, Alapakkam P. Sampath, Vladimir J. Kefalov   +3 more
wiley   +1 more source

Formal Mathematical Proof and Biophysical Phase-Attractor Model for Retinal Heptadic Layer Regeneration: The V3-RGN-09 Paradigm

outail benhadid
openalex   +1 more source

Quantifiable In Vivo Imaging Biomarkers of Retinal Regeneration by Photoreceptor Cell Transplantation. [PDF]

Transl Vis Sci Technol, 2020
Liu YV, Sodhi SK, Xue G, Teng D, Agakishiev D, McNally MM, Harris-Bookman S, McBride C, Konar GJ, Singh MS.   +9 more
europepmc   +1 more source

Channelrhodopsin ion selectivity determines mechanisms and efficacy of optogenetic defibrillation in human atria and ventricles

The Journal of Physiology, EarlyView.
Abstract figure legend A, we used in silico models of human cardiomyocytes and microelectrode recordings on transgenic zebrafish hearts to study electrophysiology during optogenetic perturbations. Specifically, we compared effects of three distinct classes of channelrhodopsins: the cation non‐selective Chlamydomonas reinhardtii channelrhodopsin‐2 (ChR2)
Sophia Ohnemus, Albert Dasí, Ahmed F. Ramadan, Joachim Greiner, Eike M. Wülfers, Matthew R. Stoyek, Linda Tillert, Johannes Vierock, T. Alexander Quinn, Peter Kohl, Patrick M. Boyle, Viviane Timmermann, Franziska Schneider‐Warme   +12 more
wiley   +1 more source

Emerging Technologies for Vision Restoration: Clinical Advances in Retinal Prostheses, Gene Therapy, Neuroprosthetics and Regenerative Ophthalmology

Lina Paola Olivero Díaz, Mikaela de Lourdes Gordillo Placencia, Ana Patricia Torres Barrios, Diego Paul Verdezoto Escobar, Melany Patricia Bolagay Apráez, Peña Armijos Jason Mauricio, Natalia Sofía Robles Cuello, Patricia Equilea Veizaga, Nilmar Del Valle Toro Arvelaiz   +8 more
openalex   +2 more sources