Results 281 to 290 of about 614,351 (314)

Retinal regeneration in amphibians

The International Journal of Developmental Biology, 1997
This review is a comparative analysis of retina regeneration in different amphibians. Special attention is given to the newt, which, unlike other vertebrates, retains the capacity for the regeneration of eye structures for all life. The review focuses on the sources of the cells which contribute to retina regeneration, proliferative activity of cells ...
openaire   +2 more sources

Retinotectal Connexions after Retinal Regeneration

Nature, 1962
IT has been shown by Sperry1 that in adult amphibians regeneration of the optic nerve fibres after rotation of the eyes through 180° about the optic axis leads to reversed visuomotor responses. It has therefore been suggested2 that there exists a cellular specificity which determines that for any given area of the retina there will be a fixed area of ...
A S, BURGEN, B, GRAFSTEIN
openaire   +2 more sources

Purinergic signaling in retinal degeneration and regeneration

Neuropharmacology, 2016
Purinergic signaling is centrally involved in mediating the degeneration of the injured and diseased retina, the induction of retinal gliosis, and the protection of the retinal tissue from degeneration. Dysregulated calcium signaling triggered by overactivation of P2X7 receptors is a crucial step in the induction of neuronal and microvascular cell ...
Andreas, Reichenbach, Andreas, Bringmann
openaire   +2 more sources

Growth Factor-Induced Retinal Regeneration in Vivo

Experimental Eye Research, 1992
It is apparent from a number of studies that the RPE has a remarkable ability to regenerate neural retina. While retinal regeneration from the RPE has not been reported in adult vertebrates, with the exception of the newt, there is evidence that many vertebrate species have the ability to regenerate a new neural retina during the early development ...
C M, Park, M J, Hollenberg
openaire   +2 more sources

Molecular regulation of retinal regeneration is context specific

2023
Abstract Many genes are known to regulate retinal regeneration following widespread tissue damage. Conversely, genes controlling regeneration following limited retinal cell loss, akin to disease conditions, are undefined.
Kevin, Emmerich, John, Hageter, Thanh, Hoang, Pin, Lyu, Abigail V, Sharrock, Anneliese, Ceisel, James, Thierer, Zeeshaan, Chunawala, Saumya, Nimmagadda, Isabella, Palazzo, Frazer, Matthews, Liyun, Zhang, David T, White, Catalina, Rodriquez, Gianna, Graziano, Patrick, Marcos, Adam, May, Tim, Mulligan, Barak, Reibman, Meera T, Saxena, David F, Ackerley, Jiang, Qian, Seth, Blackshaw, Eric, Horstick, Jeff S, Mumm   +24 more
openaire   +2 more sources

Biomaterials in Retinal Regeneration

Retinal degenerative diseases, such as age-related macular degeneration, glaucoma, retinitis pigmentosa, Leber congenital amaurosis, and Stargardt macular dystrophy, result in the progressive loss of retinal pigment epithelium, retinal ganglion cells, and photoreceptors.
E. A. Hicks, A. Monteiro, N. Tran, L. Sheardown, H. Sheardown   +4 more
openaire   +1 more source

Regeneration of Mammalian Retinal Pigment Epithelium

1994
Publisher Summary This chapter focuses on the Regeneration of mammalian retinal pigment epithelium (RPE). By regeneration it mean the replacement of the damaged RPE sheet by a new one, involving cell proliferation and migration to produce new cells that differentiate into epithelium with the structural and functional characteristics of normal RPE ...
G E, Korte, J I, Perlman, A, Pollack
openaire   +2 more sources

Unlocking retinal regeneration in mice

Science, 2020
Neurodevelopment Zebrafish can regenerate damaged retinal tissue, but mice cannot. Hoang et al. found that tracking changes in gene expression and chromatin accessibility upon injury revealed clues as to why retinal glial cells in zebrafish could generate new neurons but the same cell type in mice could not.
openaire   +1 more source

An analysis of urodelian retinal regeneration: II. Ultrastructural features of retinal regeneration in Notophthalmus viridescens

Journal of Experimental Zoology, 1973
AbstractThe process of retinal regeneration in the posterior pole of enucleated and reimplanted eyes of adult Notophthalmus viridescens was studied with the electron microscope. The posterior pigment epithelium displayed two distinct cellular types which served either as phagocytic cells or for repopulating the retina.
openaire   +2 more sources

Regeneration of retinal axons into the goldfish optic tectum

Journal of Comparative Neurology, 1976
AbstractThe growth of regenerating retinal axons into the central portion of the optic tectum of adult goldfish was examined with the light and electron microscopes. Optic tracts were cut and, two days to five months later, the animals were perfused and the tecta prepared for microscopy.
openaire   +2 more sources