Results 191 to 200 of about 17,311 (254)

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Scleral Penetration by a Cryoprobe in Primary Buckling Surgery for Traumatic Retinal Detachment: A Case Report. [PDF]

Case Rep Ophthalmol
Yamada Y, Takesue A, Yokoyama T, Kudo D, Nakao S.   +4 more
europepmc   +1 more source

Complementarity of BOLD and ADC‐fMRI in Mapping Brain Visual Processing in the Rat

NMR in Biomedicine, Volume 39, Issue 3, March 2026.
BOLD‐fMRI and ADC‐fMRI were acquired at 9.4 and 14 T during visual stimulation with variable frequency. BOLD‐fMRI showed robust positive/negative responses but depended on regional vascularization patterns. ADC‐fMRI was able to detect neural activity independently from vascular effects at 9.4 T.
Jean‐Baptiste Pérot, Andreea Hertanu, Arthur Spencer, Jasmine Nguyen‐Duc, Nikolaos Molochidis, Valerio Zerbi, Maxime Yon, Ileana Jelescu   +7 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, Volume 22, Issue 16, 17 March 2026.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Determinants of cataract types following pars plana vitrectomy: roles of underlying diseases, age, surgery duration, and silicone oil tamponade. [PDF]

BMC Ophthalmol
Ren Z, Ni Y, Ma Y, Liu L, Qin Y, Wu M.
europepmc   +1 more source

Retinal detachment in patients with Sticklers syndrome: A comprehensive analysis for craniofacial surgeons. [PDF]

JPRAS Open
Bleeker AJ, Sullivan NAT, Brouwer AH, de Koster EJ, van Egmond-Ebbeling MB, Voskuil-Kerkhof ESM, Schellekens PAW, van den Boogaard MH, Breugem CC.   +8 more
europepmc   +1 more source

Basic science in Indian ophthalmology: Translational frontiers and societal promise. [PDF]

Indian J Ophthalmol
Shetty R.
europepmc   +1 more source

Beyond Tumor Control: A Protocol for Multidimensional Assessment of Long‐Term Effects of Intensity‐Modulated Radiotherapy on Vision, Patient Well‐Being, and Morbidity in Head and Neck Cancer

Med Research, Volume 2, Issue 1, Page 190-194, March 2026.
Benjamin Abaidoo, Hannah Ayettey, Andrew Elikem Akafo, Naa N. Tagoe, Mildred Johnson, Vera Adobea Essuman, Edith Dogbe   +6 more
wiley   +1 more source

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Giant retinal tears

Survey of Ophthalmology, 2014
A giant retinal tear (GRT) is a full-thickness neurosensory retinal break that extends circumferentially around the retina for three or more clock hours in the presence of a posteriorly detached vitreous. Its incidence in large population-based studies has been estimated as 1.5% of rhegmatogenous retinal detachments, with a significant male ...
Shunmugam, Manoharan, Ang, Ghee Soon, Lois, Noemi   +2 more
openaire   +3 more sources