Results 101 to 110 of about 558,722 (284)

An effective vessel segmentation method using SLOA-HGC

open access: yesScientific Reports
Accurate segmentation of retinal blood vessels from retinal images is crucial for detecting and diagnosing a wide range of ophthalmic diseases. Our retinal blood vessel segmentation algorithm enhances microfine vessel extraction, improves edge texture ...
Zerui Liu   +9 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Twin vessels in familial retinal cavernous hemangioma

open access: yes, 1990
We investigated the presence of twin vessels in two patients and in four of their relatives at risk from one family with autosomal-dominant hereditary cavernous hemangioma of the retina associated with central nervous system involvement.
R. Canger   +3 more
core   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Retinal vasculature analysis: tuning and optimization for RETCAM images [PDF]

open access: yes, 2010
This work is focused on tuning an algorithm for the automatic detection of the retinal blood vessels. Such optimization and adaptation are aimed to allow the analysis of the vessel network in preterm babies affected by Retinophathy of Prematurity.
Cardin, Silvia
core  

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

A deep convolutional neural network-based novel class balancing for imbalance data segmentation

open access: yesScientific Reports
Retinal fundus images provide valuable insights into the human eye’s interior structure and crucial features, such as blood vessels, optic disk, macula, and fovea.
Atifa Kalsoom   +5 more
doaj   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane   +4 more
wiley   +1 more source

RETINAL DISPLACEMENT AFTER RETINECTOMY IN COMPLEX MACULA-INVOLVING RECURRENT RHEGMATOGENOUS RETINAL DETACHMENT

open access: yes
Retinectomy, essential for treating complex rhegmatogenous retinal detachment, significantly risks retinal displacement, detectable through fundus autofluorescence.
Shaheen, Abdulla   +7 more
core   +1 more source

Zebrafish ventral gastrula fate map reveals neural crest progenitor domain

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley   +1 more source

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