Results 81 to 90 of about 1,385,547 (382)

DUNet: A deformable network for retinal vessel segmentation [PDF]

open access: yesKnowledge-Based Systems, 2018
Automatic segmentation of retinal vessels in fundus images plays an important role in the diagnosis of some diseases such as diabetes and hypertension. In this paper, we propose Deformable U-Net (DUNet), which exploits the retinal vessels’ local features
Qiangguo Jin   +5 more
semanticscholar   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Repeatability and Comparability of Retinal Blood Vessel Caliber Measurements by OCTA [PDF]

open access: gold, 2023
Joby Tsai   +5 more
openalex   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

open access: yesAdvanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu   +11 more
wiley   +1 more source

Segmentation of optic disc and blood vessels in retinal images using wavelets, mathematical morphology and Hessian-based multi-scale filtering

open access: yesBiomedical Signal Processing and Control, 2017
The high importance of the accurate and early diagnostic has motivated the development of computer vision techniques of image processing and segmentation required for an completely automated assessment system for the retinal conditions.
Luiz Carlos Rodrigues, M. Marengoni
semanticscholar   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

Characterization of retinal vessels by fractal analysis: its importance in pathology

open access: yesApplied Medical Informatics, 2019
The retinal circulation is the only part of human circulation that can be directly observed by ophthalmosopy. By this assessment, a lot of connection between the appearances of retinal microcirculation has been already established.
Adriana Elena BULBOACĂ   +4 more
doaj  

Twin vessels in familial retinal cavernous hemangioma

open access: yes, 1990
We investigated the presence of twin vessels in two patients and in four of their relatives at risk from one family with autosomal-dominant hereditary cavernous hemangioma of the retina associated with central nervous system involvement.
R. Canger   +3 more
core   +1 more source

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