Results 71 to 80 of about 83,492 (257)

Establishment of an abnormal vascular patterning model in the mouse retina

Journal of Pharmacological Sciences, 2018
Abnormalities in retinal blood vessels and neuronal function persist in eyes undergoing retinopathy of prematurity. In this study, we examined morphological and functional changes in retinal blood vessels and neurons in mice that had undergone short-term
Akane Morita, Shohei Sawada, Asami Mori, Shiho Arima, Kenji Sakamoto, Tohru Nagamitsu, Tsutomu Nakahara   +6 more
doaj   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Objective Detection of Retinal Vessel Pulsation

PLOS ONE, 2015
Retinal venous pulsation detection is a subjective sign, which varies in elevated intracranial pressure, venous obstruction and glaucoma. To date no method can objectively measure and identify pulsating regions.Using high resolution video-recordings of the optic disk and retina we measured fluctuating light absorption by haemoglobin during pulsation ...
Morgan, William H., Abdul-Rahman, Anmar, Yu, Dao-Yi, Hazelton, Martin L., Betz-Stablein, Brigid, Lind, Christopher R. P.   +5 more
openaire   +7 more sources

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

ANTICARDIOLIPIN ANTIBODIES IN EYE AND NON-EYE MANIFESTATIONS OF VASCULAR DISTURBANCES IN PATIENTS WITH BEHCET’S DISEASE

Научно-практическая ревматология, 2000
Aim: Determining of possible relations between the presence of anticardiolipin antibodies (АСА) and occlusional thrombotic manifestations of Behcet’s disease(BD) Material and methods: Results of АСА study in 31 pts with BD depending on eye and other ...
N A Ermakova, Z S Alekberova, E L Nassonov   +2 more
doaj   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

An effective vessel segmentation method using SLOA-HGC

Scientific Reports
Accurate segmentation of retinal blood vessels from retinal images is crucial for detecting and diagnosing a wide range of ophthalmic diseases. Our retinal blood vessel segmentation algorithm enhances microfine vessel extraction, improves edge texture ...
Zerui Liu, Junliang Du, Weisi Dai, Wenke Zhu, Ziqing Ye, Lin Li, Zewei Liu, Linan Hu, Lin Chen, Lixiang Sun   +9 more
doaj   +1 more source